Vinyl ethers bearing the fragment RO–CH=CH2, where R is an alkyl or aryl substituent, are valuable substrates for organic synthesis and polymer chemistry. The double carbon–carbon bond is highly reactive and can be used in a wide variety of organic transformations, including addition processes—particularly cycloaddition and polymerization reactions. Recent investigations in this field have demonstrated the significant potential of subsequent transformations: vinylation of alcohols, cycloaddition of vinyl ethers, and alcohol release. Combination of these processes enables the introduction of a C2 fragment into a wide range of organic molecules. Due to these advancements, vinylation of alcohols has become a cornerstone in organic synthesis. This review focuses on an overview of important approaches to the vinylation of alcohols and highlights recent achievements in this field.
Original languageEnglish
Pages (from-to)3663-3679
Number of pages17
JournalRussian Journal of General Chemistry
Volume95
Issue number12
DOIs
StatePublished - 1 Dec 2025

    Research areas

  • acetylene, alkyne, cross-coupling, transetherification, vinyl ether, vinyl exchange, vinyl transfer, vinylation

ID: 147336834