TY - JOUR

T1 - MetaSPAdes

T2 - A new versatile metagenomic assembler

AU - Nurk, Sergey

AU - Мелешко, Дмитрий Алексеевич

AU - Korobeynikov, Anton

AU - Pevzner, Pavel A.

PY - 2017/5/1

Y1 - 2017/5/1

N2 - While metagenomics has emerged as a technology of choice for analyzing bacterial populations, the assembly of metagenomic data remains challenging, thus stifling biological discoveries. Moreover, recent studies revealed that complex bacterial populations may be composed from dozens of related strains, thus further amplifying the challenge of metagenomic assembly. metaSPAdes addresses various challenges of metagenomic assembly by capitalizing on computational ideas that proved to be useful in assemblies of single cells and highly polymorphic diploid genomes. We benchmark metaSPAdes against other state-of-the-art metagenome assemblers and demonstrate that it results in high-quality assemblies across diverse data sets.

AB - While metagenomics has emerged as a technology of choice for analyzing bacterial populations, the assembly of metagenomic data remains challenging, thus stifling biological discoveries. Moreover, recent studies revealed that complex bacterial populations may be composed from dozens of related strains, thus further amplifying the challenge of metagenomic assembly. metaSPAdes addresses various challenges of metagenomic assembly by capitalizing on computational ideas that proved to be useful in assemblies of single cells and highly polymorphic diploid genomes. We benchmark metaSPAdes against other state-of-the-art metagenome assemblers and demonstrate that it results in high-quality assemblies across diverse data sets.

UR - http://www.scopus.com/inward/record.url?scp=85019133486&partnerID=8YFLogxK

U2 - 10.1101/gr.213959.116

DO - 10.1101/gr.213959.116

M3 - Article

AN - SCOPUS:85019133486

VL - 27

SP - 824

EP - 834

JO - Genome Research

JF - Genome Research

SN - 1088-9051

IS - 5

ER -