Research output: Contribution to journal › Article › peer-review
Mast cells in photolesion of the skin and basal cell cancer associated with it. / Smirnova, I. O.; Kvetnoy, I. M.; Anichkov, N. M.; Smirnova, O. N.; Antonova, I. V.
In: Arkhiv Patologii, Vol. 67, No. 5, 06.12.2005, p. 26-29.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Mast cells in photolesion of the skin and basal cell cancer associated with it
AU - Smirnova, I. O.
AU - Kvetnoy, I. M.
AU - Anichkov, N. M.
AU - Smirnova, O. N.
AU - Antonova, I. V.
PY - 2005/12/6
Y1 - 2005/12/6
N2 - Morphofunctional features of skin mast cells located in the areas subjected to chronic UV-radiation and in the associated basal cell carcinoma with photoinjure have been studied. Various immunohistochemical methods (chromogranin A, CD1a, HLA-DR, CD35, Ki67, P53, Bcl-2, Mcl-1, involucrine) were used. It is found that chronic UV-damage leads to mast cell hyperplasia as well as activation of their synthetic, absorption and secretory functions. It is suggested that mast cell hyperplasia and increase of mast cells neuroendocrine activity provide a risk of basal cell carcinoma development.
AB - Morphofunctional features of skin mast cells located in the areas subjected to chronic UV-radiation and in the associated basal cell carcinoma with photoinjure have been studied. Various immunohistochemical methods (chromogranin A, CD1a, HLA-DR, CD35, Ki67, P53, Bcl-2, Mcl-1, involucrine) were used. It is found that chronic UV-damage leads to mast cell hyperplasia as well as activation of their synthetic, absorption and secretory functions. It is suggested that mast cell hyperplasia and increase of mast cells neuroendocrine activity provide a risk of basal cell carcinoma development.
UR - http://www.scopus.com/inward/record.url?scp=28144434063&partnerID=8YFLogxK
M3 - Article
C2 - 16323476
AN - SCOPUS:28144434063
VL - 67
SP - 26
EP - 29
JO - АРХИВ ПАТОЛОГИИ
JF - АРХИВ ПАТОЛОГИИ
SN - 0004-1955
IS - 5
ER -
ID: 49817696