TY - JOUR

T1 - Magnetite core and ZnO shell – What is in between and how does it affect on nanoparticles properties?

AU - Желтова, Виктория Витальевна

AU - Королев-Зеленый, Кирилл Владиславович

AU - Мазур, Антон Станиславович

AU - Семенов, Валентин Георгиевич

AU - Бобрышева, Наталья Петровна

AU - Осмоловский, Михаил Глебович

AU - Вознесенский, Михаил Андреевич

AU - Осмоловская, Ольга Михайловна

PY - 2023/12/30

Y1 - 2023/12/30

N2 - Fe3O4 superparamagnetic nanoparticles are one of the most promising material for MRI T2 contrast agent production. Today a problem still exist with magnetite nanoparticles stabilization and protection against the loss of magnetic properties due to the oxidation process. Present work is devoted to the study of the Fe3O4 nanoparticles with ZnO protective shell focusing on the impact of shell properties and the impact of shell synthesis conditions on magnetic properties of the obtained core–shell nanoparticles, including the formation and transformation of transition layer between magnetite and shell. Magnetic core–shell nanoparticles Fe3O4@ZnO were obtained by two different synthesis procedures at three different temperatures to impact shell formation process. All samples were thoroughly characterized with complex of physical and chemical methods, including XRD, FTIR, HR-TEM, BET, DLS, VSM and TGA-DSC measurement. Computer simulations and Mössbauer spectroscopy were engaged to understand the processes occurring between the core and the shell during the shell formation. ZnO shell was successfully synthesized over the magnetite NPs surface, the shell is thick enough to protect magnetite surface from the environment. Presence of an transition layer, which composition depends on the synthesis procedure, was revealed. Correlations between magnetic and thermal characteristics and transition layer composition were found. MRI in vitro experiments have shown that T2 relaxation times decrease with increase of shell density.

AB - Fe3O4 superparamagnetic nanoparticles are one of the most promising material for MRI T2 contrast agent production. Today a problem still exist with magnetite nanoparticles stabilization and protection against the loss of magnetic properties due to the oxidation process. Present work is devoted to the study of the Fe3O4 nanoparticles with ZnO protective shell focusing on the impact of shell properties and the impact of shell synthesis conditions on magnetic properties of the obtained core–shell nanoparticles, including the formation and transformation of transition layer between magnetite and shell. Magnetic core–shell nanoparticles Fe3O4@ZnO were obtained by two different synthesis procedures at three different temperatures to impact shell formation process. All samples were thoroughly characterized with complex of physical and chemical methods, including XRD, FTIR, HR-TEM, BET, DLS, VSM and TGA-DSC measurement. Computer simulations and Mössbauer spectroscopy were engaged to understand the processes occurring between the core and the shell during the shell formation. ZnO shell was successfully synthesized over the magnetite NPs surface, the shell is thick enough to protect magnetite surface from the environment. Presence of an transition layer, which composition depends on the synthesis procedure, was revealed. Correlations between magnetic and thermal characteristics and transition layer composition were found. MRI in vitro experiments have shown that T2 relaxation times decrease with increase of shell density.

KW - Computer simulation

KW - Contrast agent

KW - Core–shell nanoparticles

KW - Magnetic resonance imaging

KW - Magnetite

UR - https://www.mendeley.com/catalogue/2fdda742-42bb-378c-8a3d-1e8020cd3c69/

UR - http://www.scopus.com/inward/record.url?scp=85171740087&partnerID=8YFLogxK

U2 - 10.1016/j.apsusc.2023.158530

DO - 10.1016/j.apsusc.2023.158530

M3 - Article

VL - 641

JO - Applied Surface Science

JF - Applied Surface Science

SN - 0169-4332

ER -