Research output: Contribution to journal › Article › peer-review
Lokalizatsiia kompleksov kogezii v politennykh khromosomakh Drosophila melanogaster sviazana s mezhdiskami. / Markov, A. V.; Zakharov, A. A.; Galkin, A. P.; Strunnikov, A. V.; Smirnov, A. F.
In: Genetika, Vol. 39, No. 9, 09.2003, p. 1203-1211.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Lokalizatsiia kompleksov kogezii v politennykh khromosomakh Drosophila melanogaster sviazana s mezhdiskami.
AU - Markov, A. V.
AU - Zakharov, A. A.
AU - Galkin, A. P.
AU - Strunnikov, A. V.
AU - Smirnov, A. F.
PY - 2003/9
Y1 - 2003/9
N2 - The distribution of cohesin complex in polytene chromosomes of Drosophila melanogaster was studied. Cohesin is a complicated protein complex which is regulated by the DRAD21 subunit. Using immunostaining for DRAD21p, the cohesins were shown to be preferentially located in the interband regions. This specificity was not characteristic for puffs, where uniform staining was observed. The presence of a few brightly fluorescent regions (five to ten per chromosome arm) enriched with cohesin complexes was shown. Some of these regions had permanent location, and the others, variable location. No antibody binding was detected in the chromocenter. Immunostaining of interphase nuclei of neuroblasts revealed large cohesin formations. On the polytene chromosomes of D. melanogaster, the Drad21 gene was mapped to the chromocentric region (81) of the L arm of chromosome 3.
AB - The distribution of cohesin complex in polytene chromosomes of Drosophila melanogaster was studied. Cohesin is a complicated protein complex which is regulated by the DRAD21 subunit. Using immunostaining for DRAD21p, the cohesins were shown to be preferentially located in the interband regions. This specificity was not characteristic for puffs, where uniform staining was observed. The presence of a few brightly fluorescent regions (five to ten per chromosome arm) enriched with cohesin complexes was shown. Some of these regions had permanent location, and the others, variable location. No antibody binding was detected in the chromocenter. Immunostaining of interphase nuclei of neuroblasts revealed large cohesin formations. On the polytene chromosomes of D. melanogaster, the Drad21 gene was mapped to the chromocentric region (81) of the L arm of chromosome 3.
UR - http://www.scopus.com/inward/record.url?scp=0642339199&partnerID=8YFLogxK
M3 - статья
C2 - 14582389
AN - SCOPUS:0642339199
VL - 39
SP - 1203
EP - 1211
JO - ГЕНЕТИКА
JF - ГЕНЕТИКА
SN - 0016-6758
IS - 9
ER -
ID: 50510408