Local production of interleukins and growth factors in external genital endometriosis

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Local production of interleukins and growth factors in external genital endometriosis. / Sel'kov, S. A.; Solodovnikova, N. G.; Pavlov, O. V.; Niauri, D. A.

In: Bulletin of Experimental Biology and Medicine, Vol. 139, No. 4, 01.04.2005, p. 444-447.

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Author

Sel'kov, S. A. ; Solodovnikova, N. G. ; Pavlov, O. V. ; Niauri, D. A. / Local production of interleukins and growth factors in external genital endometriosis. In: Bulletin of Experimental Biology and Medicine. 2005 ; Vol. 139, No. 4. pp. 444-447.

BibTeX

@article{c870c76fda7f453fbd85108727e3a1cf,

title = "Local production of interleukins and growth factors in external genital endometriosis",

abstract = "Secretion of some IL and growth factors (VEGF, IGF-I, TGFβ) by endometrial tissues and endometrioid heterotopies was studied in vitro in patients with external genital endometriosis of different severity. The production of IL-1β, IL-2, IL-6, and VEGF in the endometrium increased in severe external genital endometriosis, while the secretion of TGFβ decreased; hyperproduction of IL-2, IL-6, VEGF and decreased production of TGFβ were detected in endometrioid foci. Presumably, local cytokine imbalance and increased proliferative activity of endometrial cells are involved in the mechanisms of formation and functioning of endometrioid foci.",

keywords = "Ectopic and endometrium, Endometriosis, Growth factors, Interleukins, Organotypic culturing",

author = "Sel'kov, {S. A.} and Solodovnikova, {N. G.} and Pavlov, {O. V.} and Niauri, {D. A.}",

year = "2005",

month = apr,

day = "1",

doi = "10.1007/s10517-005-0318-y",

language = "English",

volume = "139",

pages = "444--447",

journal = "Bulletin of Experimental Biology and Medicine",

issn = "0007-4888",

publisher = "Springer Nature",

number = "4",

}

RIS

TY - JOUR

T1 - Local production of interleukins and growth factors in external genital endometriosis

AU - Sel'kov, S. A.

AU - Solodovnikova, N. G.

AU - Pavlov, O. V.

AU - Niauri, D. A.

PY - 2005/4/1

Y1 - 2005/4/1

N2 - Secretion of some IL and growth factors (VEGF, IGF-I, TGFβ) by endometrial tissues and endometrioid heterotopies was studied in vitro in patients with external genital endometriosis of different severity. The production of IL-1β, IL-2, IL-6, and VEGF in the endometrium increased in severe external genital endometriosis, while the secretion of TGFβ decreased; hyperproduction of IL-2, IL-6, VEGF and decreased production of TGFβ were detected in endometrioid foci. Presumably, local cytokine imbalance and increased proliferative activity of endometrial cells are involved in the mechanisms of formation and functioning of endometrioid foci.

AB - Secretion of some IL and growth factors (VEGF, IGF-I, TGFβ) by endometrial tissues and endometrioid heterotopies was studied in vitro in patients with external genital endometriosis of different severity. The production of IL-1β, IL-2, IL-6, and VEGF in the endometrium increased in severe external genital endometriosis, while the secretion of TGFβ decreased; hyperproduction of IL-2, IL-6, VEGF and decreased production of TGFβ were detected in endometrioid foci. Presumably, local cytokine imbalance and increased proliferative activity of endometrial cells are involved in the mechanisms of formation and functioning of endometrioid foci.

KW - Ectopic and endometrium

KW - Endometriosis

KW - Growth factors

KW - Interleukins

KW - Organotypic culturing

UR - http://www.scopus.com/inward/record.url?scp=23644437287&partnerID=8YFLogxK

U2 - 10.1007/s10517-005-0318-y

DO - 10.1007/s10517-005-0318-y

M3 - Article

C2 - 16027877

AN - SCOPUS:23644437287

VL - 139

SP - 444

EP - 447

JO - Bulletin of Experimental Biology and Medicine

JF - Bulletin of Experimental Biology and Medicine

SN - 0007-4888

IS - 4

ER -

ID: 52392696