The effects of a current Phytophthora infestans population in Russia on genotype of Mexican tuber-bearing Solanum species were assessed in field and laboratory trials. Two-year experiments documented disease progress in 78 accessions of 19 species under high infection pressure. Detached leaf tests conducted independently in laboratories of two scientific institutions identified the response of 19 species to isolates collected in different regions of Russia. As a whole, we characterized Solanum genotypes with a broad range of resistance to late blight.