Research output: Contribution to journal › Article › peer-review
Involvement of the Arp2/3 complex and WASP proteins in the effect of glutoxim and molixan on intracellular Ca2+ concentration in macrophages. / Krutetskaya, Z.I.; Milenina, L.S.; Naumova, A.A.; Butov, S.N.; Antonov, V.G.; Nozdrachev, A.D.
In: Doklady Biochemistry and Biophysics, Vol. 464, No. 1, 2015, p. 279 - 282.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Involvement of the Arp2/3 complex and WASP proteins in the effect of glutoxim and molixan on intracellular Ca2+ concentration in macrophages
AU - Krutetskaya, Z.I.
AU - Milenina, L.S.
AU - Naumova, A.A.
AU - Butov, S.N.
AU - Antonov, V.G.
AU - Nozdrachev, A.D.
N1 - Krutetskaya Z. I., Milenina L. S., Naumova A. A., Butov S. N., Antonov V. G., Nozdrachev A. D. Involvement of the Arp2/3 complex and WASP proteins in the effect of glutoxim and molixan on intracellular Ca2+ concentration in macrophages // Doklady Biochemistry and Biophysics, 2015. — Vol. 464, — P. 279-282
PY - 2015
Y1 - 2015
N2 - © 2015, Pleiades Publishing, Ltd.The Fura-2AM fluorescent Ca2+ probe was used to study the possibility that the Arp2/3 complex and WASP proteins are involved in the effects of glutoxim and molixan on the intracellular Ca2+ concentration in macrophages. It has been demonstrated that preincubation of macrophages with inhibitors of the Arp2/3 complex or WASP proteins (CK-0944666 or wiskostatin, respectively) results in a significant suppression of Ca2+-responses induced by glutoxim or molixan. This suggests that polymerization of actin filaments is a process involved in the effect of glutoxim or molixan on intracellular Ca2+ concentration in macrophages.
AB - © 2015, Pleiades Publishing, Ltd.The Fura-2AM fluorescent Ca2+ probe was used to study the possibility that the Arp2/3 complex and WASP proteins are involved in the effects of glutoxim and molixan on the intracellular Ca2+ concentration in macrophages. It has been demonstrated that preincubation of macrophages with inhibitors of the Arp2/3 complex or WASP proteins (CK-0944666 or wiskostatin, respectively) results in a significant suppression of Ca2+-responses induced by glutoxim or molixan. This suggests that polymerization of actin filaments is a process involved in the effect of glutoxim or molixan on intracellular Ca2+ concentration in macrophages.
U2 - 10.1134/S1607672955050013
DO - 10.1134/S1607672955050013
M3 - Article
VL - 464
SP - 279
EP - 282
JO - Doklady Biochemistry and Biophysics
JF - Doklady Biochemistry and Biophysics
SN - 1607-6729
IS - 1
ER -
ID: 3947154