Research output: Contribution to journal › Article › peer-review
Investigation of the radioprotective properties of some tea polyphenols. / Ershov, D.S.; Paston, S.V.; Kartsova, L.A.; Alekseeva, A.V.; Ganzha, O.V.; Kasyanenko, N.A.
In: Structural Chemistry, Vol. 22, No. 2, 2011, p. 475-482.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Investigation of the radioprotective properties of some tea polyphenols.
AU - Ershov, D.S.
AU - Paston, S.V.
AU - Kartsova, L.A.
AU - Alekseeva, A.V.
AU - Ganzha, O.V.
AU - Kasyanenko, N.A.
PY - 2011
Y1 - 2011
N2 - The influence of tea and coffee flavonoids (-)-epicatechin (EC) and (+)-catechin (C) on the effect of gamma-irradiation of DNA molecules in solutions was investigated. The concentrations of these and other components in different samples of black and green tea were analyzed by the capillary electrophoresis. It was determined from the experimental data obtained by different methods (circular dichroism and UV spectra, viscosimetry and optical investigations) that C and EC do not form complexes with DNA in solutions. It was shown that C and EC have radioprotective properties, being scavengers of the water radiolysis products.
AB - The influence of tea and coffee flavonoids (-)-epicatechin (EC) and (+)-catechin (C) on the effect of gamma-irradiation of DNA molecules in solutions was investigated. The concentrations of these and other components in different samples of black and green tea were analyzed by the capillary electrophoresis. It was determined from the experimental data obtained by different methods (circular dichroism and UV spectra, viscosimetry and optical investigations) that C and EC do not form complexes with DNA in solutions. It was shown that C and EC have radioprotective properties, being scavengers of the water radiolysis products.
KW - DNA damage
KW - Gamma radiation
KW - Aqueous solutions
KW - Flavonoids
KW - Ultraviolet spectrophotometry
KW - Circular dichroism
KW - Viscosity
KW - Atomic force microscopy
KW - INDUCED DNA-DAMAGE
KW - GREEN TEA
KW - DEOXYRIBONUCLEIC-ACID
KW - GAMMA-IRRADIATION
KW - STRAND BREAKS
KW - CATECHINS
KW - CONFORMATION
KW - MOLECULE
KW - PLASMID
KW - GROWTH
U2 - 10.1007/s11224-011-9765-4
DO - 10.1007/s11224-011-9765-4
M3 - Article
VL - 22
SP - 475
EP - 482
JO - Structural Chemistry
JF - Structural Chemistry
SN - 1040-0400
IS - 2
ER -
ID: 5115164