Research output: Contribution to journal › Article › peer-review
Investigation of DNA complexes with iron ions in solution. / Kasyanenko, N.; Arikainen, N.; Frisman, E.
In: Biophysical Chemistry, Vol. 70, No. 2, 16.02.1998, p. 93-100.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Investigation of DNA complexes with iron ions in solution
AU - Kasyanenko, N.
AU - Arikainen, N.
AU - Frisman, E.
PY - 1998/2/16
Y1 - 1998/2/16
N2 - The optical anisotropy and intrinsic viscosity of DNA-Fe3+ complexes have been investigated. It was shown that the binding of iron ions to DNA causes the shrinkage of the macromolecule. The formation of such complexes is accompanied by increasing DNA optical anisotropy. We suggest that the binding of iron ions to widely spaced along the chain DNA groups creates the conditions for initiation of mutually oriented DNA fragments, thus, ensuring a higher molecular optical anisotropy.
AB - The optical anisotropy and intrinsic viscosity of DNA-Fe3+ complexes have been investigated. It was shown that the binding of iron ions to DNA causes the shrinkage of the macromolecule. The formation of such complexes is accompanied by increasing DNA optical anisotropy. We suggest that the binding of iron ions to widely spaced along the chain DNA groups creates the conditions for initiation of mutually oriented DNA fragments, thus, ensuring a higher molecular optical anisotropy.
KW - DNA-Fe complexes
KW - Intrinsic viscosity
KW - Optical anisotropy
UR - http://www.scopus.com/inward/record.url?scp=0032536510&partnerID=8YFLogxK
U2 - 10.1016/S0301-4622(97)00111-7
DO - 10.1016/S0301-4622(97)00111-7
M3 - Article
C2 - 9540202
AN - SCOPUS:0032536510
VL - 70
SP - 93
EP - 100
JO - Biophysical Chemistry
JF - Biophysical Chemistry
SN - 0301-4622
IS - 2
ER -
ID: 73393364