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Interspecific Differences in Behavioral Responses and Neuromotorics between Laboratory Rodents Receiving Rations with Easily Digested Carbohydrates. / Apryatin, S. A.; Shipelin, V. A.; Sidorova, Yu S.; Petrov, N. A.; Gmoshinskii, I. V.; Nikityuk, D. B.

In: Bulletin of Experimental Biology and Medicine, Vol. 165, No. 1, 01.05.2018, p. 5-9.

Research output: Contribution to journalArticlepeer-review

Harvard

Apryatin, SA, Shipelin, VA, Sidorova, YS, Petrov, NA, Gmoshinskii, IV & Nikityuk, DB 2018, 'Interspecific Differences in Behavioral Responses and Neuromotorics between Laboratory Rodents Receiving Rations with Easily Digested Carbohydrates', Bulletin of Experimental Biology and Medicine, vol. 165, no. 1, pp. 5-9. https://doi.org/10.1007/s10517-018-4086-x

APA

Apryatin, S. A., Shipelin, V. A., Sidorova, Y. S., Petrov, N. A., Gmoshinskii, I. V., & Nikityuk, D. B. (2018). Interspecific Differences in Behavioral Responses and Neuromotorics between Laboratory Rodents Receiving Rations with Easily Digested Carbohydrates. Bulletin of Experimental Biology and Medicine, 165(1), 5-9. https://doi.org/10.1007/s10517-018-4086-x

Vancouver

Apryatin SA, Shipelin VA, Sidorova YS, Petrov NA, Gmoshinskii IV, Nikityuk DB. Interspecific Differences in Behavioral Responses and Neuromotorics between Laboratory Rodents Receiving Rations with Easily Digested Carbohydrates. Bulletin of Experimental Biology and Medicine. 2018 May 1;165(1):5-9. https://doi.org/10.1007/s10517-018-4086-x

Author

Apryatin, S. A. ; Shipelin, V. A. ; Sidorova, Yu S. ; Petrov, N. A. ; Gmoshinskii, I. V. ; Nikityuk, D. B. / Interspecific Differences in Behavioral Responses and Neuromotorics between Laboratory Rodents Receiving Rations with Easily Digested Carbohydrates. In: Bulletin of Experimental Biology and Medicine. 2018 ; Vol. 165, No. 1. pp. 5-9.

BibTeX

@article{ef141c51f3604f23a5400c61ad40a13a,
title = "Interspecific Differences in Behavioral Responses and Neuromotorics between Laboratory Rodents Receiving Rations with Easily Digested Carbohydrates",
abstract = "We assessed the effect of intake of easily digested carbohydrates for 133 days on quantitative parameters of neuromotorics and cognitive function in Wistar rats and C57Bl/6J mice. Neuromotorics (muscle tone) was assessed in rats and mice by the forelimb muscle force (grip strength) over 4 months. Anxiety was assessed in the elevated plus-maze test and cognitive function (short-term and long-term memory) was evaluated by conditioned passive avoidance response (CPAR) test over 3 months. The mice, in contrast to rats, receiving the diet with easily digested sugars demonstrated suppression of neuromotorics. Anxiety increased with age in female mice, but not in rats, irrespective of the diet. Cognitive function in rats receiving experimental rations did not change significantly in comparison with the control. In mice, consumption of equimolar mixture of fructose and glucose impared short-term, but not long-term memory, in comparison with the group receiving glucose alone. We revealed a small (by 14-17%), but statistically significant increase in the brain weight in mice receiving fructose and sucrose. The study demonstrates sufficient interspecies differences in the influence of carbohydrate rations on neuromotorics and behavioral responses in the in vivo metabolic syndrome model.",
keywords = "behavioral responses, in vivo models, metabolic syndrome, mice, rats",
author = "Apryatin, {S. A.} and Shipelin, {V. A.} and Sidorova, {Yu S.} and Petrov, {N. A.} and Gmoshinskii, {I. V.} and Nikityuk, {D. B.}",
year = "2018",
month = may,
day = "1",
doi = "10.1007/s10517-018-4086-x",
language = "English",
volume = "165",
pages = "5--9",
journal = "Bulletin of Experimental Biology and Medicine",
issn = "0007-4888",
publisher = "Springer Nature",
number = "1",

}

RIS

TY - JOUR

T1 - Interspecific Differences in Behavioral Responses and Neuromotorics between Laboratory Rodents Receiving Rations with Easily Digested Carbohydrates

AU - Apryatin, S. A.

AU - Shipelin, V. A.

AU - Sidorova, Yu S.

AU - Petrov, N. A.

AU - Gmoshinskii, I. V.

AU - Nikityuk, D. B.

PY - 2018/5/1

Y1 - 2018/5/1

N2 - We assessed the effect of intake of easily digested carbohydrates for 133 days on quantitative parameters of neuromotorics and cognitive function in Wistar rats and C57Bl/6J mice. Neuromotorics (muscle tone) was assessed in rats and mice by the forelimb muscle force (grip strength) over 4 months. Anxiety was assessed in the elevated plus-maze test and cognitive function (short-term and long-term memory) was evaluated by conditioned passive avoidance response (CPAR) test over 3 months. The mice, in contrast to rats, receiving the diet with easily digested sugars demonstrated suppression of neuromotorics. Anxiety increased with age in female mice, but not in rats, irrespective of the diet. Cognitive function in rats receiving experimental rations did not change significantly in comparison with the control. In mice, consumption of equimolar mixture of fructose and glucose impared short-term, but not long-term memory, in comparison with the group receiving glucose alone. We revealed a small (by 14-17%), but statistically significant increase in the brain weight in mice receiving fructose and sucrose. The study demonstrates sufficient interspecies differences in the influence of carbohydrate rations on neuromotorics and behavioral responses in the in vivo metabolic syndrome model.

AB - We assessed the effect of intake of easily digested carbohydrates for 133 days on quantitative parameters of neuromotorics and cognitive function in Wistar rats and C57Bl/6J mice. Neuromotorics (muscle tone) was assessed in rats and mice by the forelimb muscle force (grip strength) over 4 months. Anxiety was assessed in the elevated plus-maze test and cognitive function (short-term and long-term memory) was evaluated by conditioned passive avoidance response (CPAR) test over 3 months. The mice, in contrast to rats, receiving the diet with easily digested sugars demonstrated suppression of neuromotorics. Anxiety increased with age in female mice, but not in rats, irrespective of the diet. Cognitive function in rats receiving experimental rations did not change significantly in comparison with the control. In mice, consumption of equimolar mixture of fructose and glucose impared short-term, but not long-term memory, in comparison with the group receiving glucose alone. We revealed a small (by 14-17%), but statistically significant increase in the brain weight in mice receiving fructose and sucrose. The study demonstrates sufficient interspecies differences in the influence of carbohydrate rations on neuromotorics and behavioral responses in the in vivo metabolic syndrome model.

KW - behavioral responses

KW - in vivo models

KW - metabolic syndrome

KW - mice

KW - rats

UR - http://www.scopus.com/inward/record.url?scp=85047336047&partnerID=8YFLogxK

U2 - 10.1007/s10517-018-4086-x

DO - 10.1007/s10517-018-4086-x

M3 - Article

C2 - 29797123

AN - SCOPUS:85047336047

VL - 165

SP - 5

EP - 9

JO - Bulletin of Experimental Biology and Medicine

JF - Bulletin of Experimental Biology and Medicine

SN - 0007-4888

IS - 1

ER -

ID: 115017749