Interaction of Platinum Compounds PtenCl2 and [Pten Cl SO(CH3)2] NO3 with DNA Molecule in Solution

DOI

https://doi.org/10.1088/1742-6596/1172/1/012105
Final published version
https://doi.org/10.1088/1742-6596/1172/1/012105
Final published version

Yu V. Sharikhina
N. A. Kasyanenko

It was demonstrated that the replacement of chlorine ion on dimethyl sulfoxide (DMSO) in the first coordination sphere of platinum changes the result of compound interaction with DNA. DMSO molecule blocks one of the active centers of the platinum compound participating in the formation of coordination bonds with macromolecule, and DNA does not substitute DMSO molecule in the platinum first coordination sphere.

Original language	English
Title of host publication	INTERNATIONAL CONFERENCE ON APPLIED PHYSICS, POWER AND MATERIAL SCIENCE
Publisher	IOP Publishing Ltd.
Number of pages	6
Edition	1
DOIs	https://doi.org/10.1088/1742-6596/1172/1/012105 https://doi.org/10.1088/1742-6596/1172/1/012105
State	Published - 1 Apr 2019
Event	International Conference on Applied Physics, Power and Material Science 2018, ICAPPM 2018 - Secunderabad, Telangana, India Duration: 5 Dec 2018 → 6 Dec 2018

Publication series

Name	Journal of Physics: Conference Series
Publisher	IOP Publishing Ltd.
Volume	1172
ISSN (Print)	1742-6588

Conference

Conference	International Conference on Applied Physics, Power and Material Science 2018, ICAPPM 2018
Country/Territory	India
City	Secunderabad, Telangana
Period	5/12/18 → 6/12/18

Scopus subject areas

Physics and Astronomy(all)

Research areas

calf, circular, compounds, dichroism, dimethyl, DNA, hydrodynamic, platinum, properties, sulfoxide, thymus

ID: 73402471