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Inflammatory Bowel Disease: Crosstalk between Histamine, Immunity, and Disease. / Дворникова, Кристина Алексеевна; Платонова, Ольга Николаевна; Быстрова, Елена Юрьевна.

In: International Journal of Molecular Sciences, Vol. 24, No. 12, 9937, 09.06.2023.

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@article{bee9e7f231b64b8cb5b0987d916bde14,
title = "Inflammatory Bowel Disease: Crosstalk between Histamine, Immunity, and Disease",
abstract = "Inflammatory bowel disease (IBD) is increasingly recognized as a serious, worldwide public health concern. It is generally acknowledged that a variety of factors play a role in the pathogenesis of this group of chronic inflammatory diseases. The diversity of molecular actors involved in IBD does not allow us to fully assess the causal relationships existing in such interactions. Given the high immunomodulatory activity of histamine and the complex immune-mediated nature of inflammatory bowel disease, the role of histamine and its receptors in the gut may be significant. This paper has been prepared to provide a schematic of the most important and possible molecular signaling pathways related to histamine and its receptors and to assess their relevance for the development of therapeutic approaches.",
keywords = "Cell Physiological Phenomena, Colitis, Ulcerative/metabolism, Histamine, Humans, Inflammatory Bowel Diseases/metabolism",
author = "Дворникова, {Кристина Алексеевна} and Платонова, {Ольга Николаевна} and Быстрова, {Елена Юрьевна}",
year = "2023",
month = jun,
day = "9",
doi = "10.3390/ijms24129937",
language = "English",
volume = "24",
journal = "International Journal of Molecular Sciences",
issn = "1422-0067",
publisher = "MDPI AG",
number = "12",

}

RIS

TY - JOUR

T1 - Inflammatory Bowel Disease: Crosstalk between Histamine, Immunity, and Disease

AU - Дворникова, Кристина Алексеевна

AU - Платонова, Ольга Николаевна

AU - Быстрова, Елена Юрьевна

PY - 2023/6/9

Y1 - 2023/6/9

N2 - Inflammatory bowel disease (IBD) is increasingly recognized as a serious, worldwide public health concern. It is generally acknowledged that a variety of factors play a role in the pathogenesis of this group of chronic inflammatory diseases. The diversity of molecular actors involved in IBD does not allow us to fully assess the causal relationships existing in such interactions. Given the high immunomodulatory activity of histamine and the complex immune-mediated nature of inflammatory bowel disease, the role of histamine and its receptors in the gut may be significant. This paper has been prepared to provide a schematic of the most important and possible molecular signaling pathways related to histamine and its receptors and to assess their relevance for the development of therapeutic approaches.

AB - Inflammatory bowel disease (IBD) is increasingly recognized as a serious, worldwide public health concern. It is generally acknowledged that a variety of factors play a role in the pathogenesis of this group of chronic inflammatory diseases. The diversity of molecular actors involved in IBD does not allow us to fully assess the causal relationships existing in such interactions. Given the high immunomodulatory activity of histamine and the complex immune-mediated nature of inflammatory bowel disease, the role of histamine and its receptors in the gut may be significant. This paper has been prepared to provide a schematic of the most important and possible molecular signaling pathways related to histamine and its receptors and to assess their relevance for the development of therapeutic approaches.

KW - Cell Physiological Phenomena

KW - Colitis, Ulcerative/metabolism

KW - Histamine

KW - Humans

KW - Inflammatory Bowel Diseases/metabolism

UR - https://www.mendeley.com/catalogue/9f9ed8bf-64d0-3b5d-b7f7-12662d4dadec/

U2 - 10.3390/ijms24129937

DO - 10.3390/ijms24129937

M3 - Review article

C2 - 37373085

VL - 24

JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

SN - 1422-0067

IS - 12

M1 - 9937

ER -

ID: 108770013