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In Vivo Production of RNA Aptamers and Nanoparticles : Problems and Prospects. / Shanaa, Ousama Al; Rumyantsev, Andrey; Sambuk, Elena; Padkina, Marina.

In: Molecules, Vol. 26, No. 5, 1422, 06.03.2021, p. 1422-1440.

Research output: Contribution to journal › Review article › peer-review

Harvard

Shanaa, OA, Rumyantsev, A, Sambuk, E & Padkina, M 2021, 'In Vivo Production of RNA Aptamers and Nanoparticles: Problems and Prospects', Molecules, vol. 26, no. 5, 1422, pp. 1422-1440. https://doi.org/10.3390/molecules26051422

APA

Shanaa, O. A., Rumyantsev, A., Sambuk, E., & Padkina, M. (2021). In Vivo Production of RNA Aptamers and Nanoparticles: Problems and Prospects. Molecules, 26(5), 1422-1440. [1422]. https://doi.org/10.3390/molecules26051422

Vancouver

Shanaa OA, Rumyantsev A, Sambuk E, Padkina M. In Vivo Production of RNA Aptamers and Nanoparticles: Problems and Prospects. Molecules. 2021 Mar 6;26(5):1422-1440. 1422. https://doi.org/10.3390/molecules26051422

Author

Shanaa, Ousama Al ; Rumyantsev, Andrey ; Sambuk, Elena ; Padkina, Marina. / In Vivo Production of RNA Aptamers and Nanoparticles : Problems and Prospects. In: Molecules. 2021 ; Vol. 26, No. 5. pp. 1422-1440.

BibTeX

@article{b6e176592a8f4ab09489797c0572f91b,
title = "In Vivo Production of RNA Aptamers and Nanoparticles: Problems and Prospects",
abstract = "RNA aptamers are becoming increasingly attractive due to their superior properties. This review discusses the early stages of aptamer research, the main developments in this area, and the latest technologies being developed. The review also highlights the advantages of RNA aptamers in comparison to antibodies, considering the great potential of RNA aptamers and their applications in the near future. In addition, it is shown how RNA aptamers can form endless 3-D structures, giving rise to various structural and functional possibilities. Special attention is paid to the Mango, Spinach and Broccoli fluorescent RNA aptamers, and the advantages of split RNA aptamers are discussed. The review focuses on the importance of creating a platform for the synthesis of RNA nanoparticles in vivo and examines yeast, namely Saccharomyces cerevisiae, as a potential model organism for the production of RNA nanoparticles on a large scale.",
keywords = "aptamer, nanoparticles, nucleic acid nanoparticles, nucleic acids",
author = "Shanaa, {Ousama Al} and Andrey Rumyantsev and Elena Sambuk and Marina Padkina",
note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2021",
month = mar,
day = "6",
doi = "10.3390/molecules26051422",
language = "English",
volume = "26",
pages = "1422--1440",
journal = "Molecules",
issn = "1420-3049",
publisher = "MDPI AG",
number = "5",

}

RIS

TY - JOUR

T1 - In Vivo Production of RNA Aptamers and Nanoparticles

T2 - Problems and Prospects

AU - Shanaa, Ousama Al

AU - Rumyantsev, Andrey

AU - Sambuk, Elena

AU - Padkina, Marina

N1 - Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2021/3/6

Y1 - 2021/3/6

N2 - RNA aptamers are becoming increasingly attractive due to their superior properties. This review discusses the early stages of aptamer research, the main developments in this area, and the latest technologies being developed. The review also highlights the advantages of RNA aptamers in comparison to antibodies, considering the great potential of RNA aptamers and their applications in the near future. In addition, it is shown how RNA aptamers can form endless 3-D structures, giving rise to various structural and functional possibilities. Special attention is paid to the Mango, Spinach and Broccoli fluorescent RNA aptamers, and the advantages of split RNA aptamers are discussed. The review focuses on the importance of creating a platform for the synthesis of RNA nanoparticles in vivo and examines yeast, namely Saccharomyces cerevisiae, as a potential model organism for the production of RNA nanoparticles on a large scale.

AB - RNA aptamers are becoming increasingly attractive due to their superior properties. This review discusses the early stages of aptamer research, the main developments in this area, and the latest technologies being developed. The review also highlights the advantages of RNA aptamers in comparison to antibodies, considering the great potential of RNA aptamers and their applications in the near future. In addition, it is shown how RNA aptamers can form endless 3-D structures, giving rise to various structural and functional possibilities. Special attention is paid to the Mango, Spinach and Broccoli fluorescent RNA aptamers, and the advantages of split RNA aptamers are discussed. The review focuses on the importance of creating a platform for the synthesis of RNA nanoparticles in vivo and examines yeast, namely Saccharomyces cerevisiae, as a potential model organism for the production of RNA nanoparticles on a large scale.

KW - aptamer

KW - nanoparticles

KW - nucleic acid nanoparticles

KW - nucleic acids

UR - http://www.scopus.com/inward/record.url?scp=85103863354&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/f99be2ee-d4b3-381c-aef5-f2f9421abe22/

U2 - 10.3390/molecules26051422

DO - 10.3390/molecules26051422

M3 - Review article

C2 - 33800717

AN - SCOPUS:85103863354

VL - 26

SP - 1422

EP - 1440

JO - Molecules

JF - Molecules

SN - 1420-3049

IS - 5

M1 - 1422

ER -

ID: 75543453