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Imbalance in memory B-cells in patients with pulmonary sarcoidosis. / Zinchenko, U.; Kudryavtsev, I.; Starshinova, A.; Basantsova, N.; Serebriakova, M.; Malkova, A.; Toubi, E.; Churilov, L.; Yablonskiy, P.

In: European Respiratory Journal, Supplement, Vol. 54, No. S63, 2019, p. PA4096.

Research output: Contribution to journalArticle

Harvard

Zinchenko, U, Kudryavtsev, I, Starshinova, A, Basantsova, N, Serebriakova, M, Malkova, A, Toubi, E, Churilov, L & Yablonskiy, P 2019, 'Imbalance in memory B-cells in patients with pulmonary sarcoidosis.', European Respiratory Journal, Supplement, vol. 54, no. S63, pp. PA4096. <http://elibrary.ru/item.asp?id=41451327>

APA

Zinchenko, U., Kudryavtsev, I., Starshinova, A., Basantsova, N., Serebriakova, M., Malkova, A., Toubi, E., Churilov, L., & Yablonskiy, P. (2019). Imbalance in memory B-cells in patients with pulmonary sarcoidosis. European Respiratory Journal, Supplement, 54(S63), PA4096. http://elibrary.ru/item.asp?id=41451327

Vancouver

Zinchenko U, Kudryavtsev I, Starshinova A, Basantsova N, Serebriakova M, Malkova A et al. Imbalance in memory B-cells in patients with pulmonary sarcoidosis. European Respiratory Journal, Supplement. 2019;54(S63):PA4096.

Author

Zinchenko, U. ; Kudryavtsev, I. ; Starshinova, A. ; Basantsova, N. ; Serebriakova, M. ; Malkova, A. ; Toubi, E. ; Churilov, L. ; Yablonskiy, P. / Imbalance in memory B-cells in patients with pulmonary sarcoidosis. In: European Respiratory Journal, Supplement. 2019 ; Vol. 54, No. S63. pp. PA4096.

BibTeX

@article{8054bc915058427f8883949a4d75383c,
title = "Imbalance in memory B-cells in patients with pulmonary sarcoidosis.",
abstract = "Introduction: Sarcoidosis (SD) is considered to be a T-cell-driven disorder, but recent studies show also B-cells participation in SD (Musaelyan, 2018; Saussine, 2012). The aim was to determine the different subsets of memory B-cells in SD. Methods: A prospective comparative study was conducted in 2016-2018 with examination of patients with SD (n=37) and healthy control (HC) (n=35). 200 μL of whole blood were stained on surface with fluorochrome-conjugated monoclonal antibodies: anti-IgD Alexa Fluor 488 (clone IA6-2, isotype - Mouse IgG2a, κ), anti-CD38 PE (clone LS198-4-3, isotype - IgG1 Mouse). IgD, CD19 - BioLegend, Inc. (USA), CD38 - Beckman Coulter, Inc (USA). Sample acquisition was performed with a Navios flow cytometer (Beckman Coulter, Inc., USA). Supported by Russian Federation Government Grant (contract N14.W03.31.0009 of 13.02.2017). Results: The frequency of B cells in SD was significantly higher than in HC (14.48% (9.86; 17.29) vs 11.09% (8.52; 13.28), p=0.008). “Activated naive” Bm2 cells and pr",
author = "U. Zinchenko and I. Kudryavtsev and A. Starshinova and N. Basantsova and M. Serebriakova and A. Malkova and E. Toubi and L. Churilov and P. Yablonskiy",
year = "2019",
language = "English",
volume = "54",
pages = "PA4096",
journal = "European Respiratory Journal, Supplement",
issn = "0904-1850",
publisher = "European Respiratory Society",
number = "S63",

}

RIS

TY - JOUR

T1 - Imbalance in memory B-cells in patients with pulmonary sarcoidosis.

AU - Zinchenko, U.

AU - Kudryavtsev, I.

AU - Starshinova, A.

AU - Basantsova, N.

AU - Serebriakova, M.

AU - Malkova, A.

AU - Toubi, E.

AU - Churilov, L.

AU - Yablonskiy, P.

PY - 2019

Y1 - 2019

N2 - Introduction: Sarcoidosis (SD) is considered to be a T-cell-driven disorder, but recent studies show also B-cells participation in SD (Musaelyan, 2018; Saussine, 2012). The aim was to determine the different subsets of memory B-cells in SD. Methods: A prospective comparative study was conducted in 2016-2018 with examination of patients with SD (n=37) and healthy control (HC) (n=35). 200 μL of whole blood were stained on surface with fluorochrome-conjugated monoclonal antibodies: anti-IgD Alexa Fluor 488 (clone IA6-2, isotype - Mouse IgG2a, κ), anti-CD38 PE (clone LS198-4-3, isotype - IgG1 Mouse). IgD, CD19 - BioLegend, Inc. (USA), CD38 - Beckman Coulter, Inc (USA). Sample acquisition was performed with a Navios flow cytometer (Beckman Coulter, Inc., USA). Supported by Russian Federation Government Grant (contract N14.W03.31.0009 of 13.02.2017). Results: The frequency of B cells in SD was significantly higher than in HC (14.48% (9.86; 17.29) vs 11.09% (8.52; 13.28), p=0.008). “Activated naive” Bm2 cells and pr

AB - Introduction: Sarcoidosis (SD) is considered to be a T-cell-driven disorder, but recent studies show also B-cells participation in SD (Musaelyan, 2018; Saussine, 2012). The aim was to determine the different subsets of memory B-cells in SD. Methods: A prospective comparative study was conducted in 2016-2018 with examination of patients with SD (n=37) and healthy control (HC) (n=35). 200 μL of whole blood were stained on surface with fluorochrome-conjugated monoclonal antibodies: anti-IgD Alexa Fluor 488 (clone IA6-2, isotype - Mouse IgG2a, κ), anti-CD38 PE (clone LS198-4-3, isotype - IgG1 Mouse). IgD, CD19 - BioLegend, Inc. (USA), CD38 - Beckman Coulter, Inc (USA). Sample acquisition was performed with a Navios flow cytometer (Beckman Coulter, Inc., USA). Supported by Russian Federation Government Grant (contract N14.W03.31.0009 of 13.02.2017). Results: The frequency of B cells in SD was significantly higher than in HC (14.48% (9.86; 17.29) vs 11.09% (8.52; 13.28), p=0.008). “Activated naive” Bm2 cells and pr

M3 - Article

VL - 54

SP - PA4096

JO - European Respiratory Journal, Supplement

JF - European Respiratory Journal, Supplement

SN - 0904-1850

IS - S63

ER -

ID: 78450385