Hypoglycemic Potential of Benzimidazole Derivatives. / Spasov, A. A.; Lenskaya, K. V.; Vasil’ev, P. M.
In: Pharmaceutical Chemistry Journal, Vol. 49, No. 8, 01.11.2015, p. 495-500.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Hypoglycemic Potential of Benzimidazole Derivatives
AU - Spasov, A. A.
AU - Lenskaya, K. V.
AU - Vasil’ev, P. M.
N1 - Publisher Copyright: © 2015, Springer Science+Business Media New York. Copyright: Copyright 2016 Elsevier B.V., All rights reserved.
PY - 2015/11/1
Y1 - 2015/11/1
N2 - Benzimidazole derivatives exhibiting hypoglycemic and antidiabetic properties were reviewed. Activities of compounds from 22 classes of substituted benzimidazoles and their tricyclic condensed analogs were presented. The structures of compounds acting on various diabetic targets were discussed with respect to antidiabetic activity. Information of potential use for the synthesis and discovery of new targeted antidiabetic drugs was provided.
AB - Benzimidazole derivatives exhibiting hypoglycemic and antidiabetic properties were reviewed. Activities of compounds from 22 classes of substituted benzimidazoles and their tricyclic condensed analogs were presented. The structures of compounds acting on various diabetic targets were discussed with respect to antidiabetic activity. Information of potential use for the synthesis and discovery of new targeted antidiabetic drugs was provided.
KW - antidiabetic activity
KW - benzimidazole derivatives
KW - hypoglycemic activity
KW - tricyclic benzimidazole derivatives
UR - http://www.scopus.com/inward/record.url?scp=84957430627&partnerID=8YFLogxK
U2 - 10.1007/s11094-015-1313-x
DO - 10.1007/s11094-015-1313-x
M3 - Article
AN - SCOPUS:84957430627
VL - 49
SP - 495
EP - 500
JO - Pharmaceutical Chemistry Journal
JF - Pharmaceutical Chemistry Journal
SN - 0091-150X
IS - 8
ER -
ID: 62841121