This article analyzes current problems associated with surgical and systemic treatment for hereditary breast and ovarian cancers (including those associated with BRCA1/2 gene mutations). We discuss the issues related to clinical course of multiple primary tumors and their sensitivity to cytostatic and targeted therapy.

Original languageEnglish
Pages (from-to)54-65
Number of pages12
JournalOpuholi Zenskoj Reproduktivnoj Sistemy
Volume16
Issue number4
DOIs
StatePublished - 2020

    Research areas

  • BRCA1, BRCA2, Breast cancer, CHEK2, Multiple primary tumors, Ovarian cancer, PARP inhibitors

    Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology
  • Pharmacology (medical)
  • Radiology Nuclear Medicine and imaging
  • Surgery

ID: 88554169