Research output: Contribution to journal › Article › peer-review
Graphene oxide enriched with oxygen-containing groups: on the way to an increase of antioxidant activity and biocompatibility. / Абделхалим, Абделсаттар Осама Елемам; Мещеряков, Анатолий Анатольевич; Майстренко, Дмитрий Николаевич; Молчанов, Олег Евгеньевич; Агеев, Сергей Вадимович; Иванова, Дарья Андреевна; Ямалова, Наиля Рашитовна; Лутцев, Михаил Денисович; Васина, Любовь Васильевна; Шаройко, Владимир Владимирович; Семёнов, Константин Николаевич.
In: Colloids and Surfaces B: Biointerfaces, 20.11.2021.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Graphene oxide enriched with oxygen-containing groups: on the way to an increase of antioxidant activity and biocompatibility
AU - Абделхалим, Абделсаттар Осама Елемам
AU - Мещеряков, Анатолий Анатольевич
AU - Майстренко, Дмитрий Николаевич
AU - Молчанов, Олег Евгеньевич
AU - Агеев, Сергей Вадимович
AU - Иванова, Дарья Андреевна
AU - Ямалова, Наиля Рашитовна
AU - Лутцев, Михаил Денисович
AU - Васина, Любовь Васильевна
AU - Шаройко, Владимир Владимирович
AU - Семёнов, Константин Николаевич
N1 - Publisher Copyright: © 2021 Elsevier B.V.
PY - 2021/11/20
Y1 - 2021/11/20
N2 - The article is dedicated to the comprehensive biocompatibility investigation of synthesised graphene oxide (GO) enriched with oxygen-containing functional groups (⁓85%). GO was synthesised through a modified Hummers and Offeman's method and characterised using 13C NMR, Raman, and IR spectroscopy, XRD, HRTEM, along with size dimensions and ζ-potentials in aqueous dispersions. Biocompatibility study included tests on haemocompatibility (haemolysis, platelet aggregation, binding to human serum albumin and its esterase activity), antioxidant activity (2,2-diphenyl-1-picrylhydrazyl reaction, NO-radical uptake, Radachlorin photobleaching, photo-induced haemolysis), genotoxicity using DNA comet assay, as well as metabolic activity and proliferation of HEK293 cells.
AB - The article is dedicated to the comprehensive biocompatibility investigation of synthesised graphene oxide (GO) enriched with oxygen-containing functional groups (⁓85%). GO was synthesised through a modified Hummers and Offeman's method and characterised using 13C NMR, Raman, and IR spectroscopy, XRD, HRTEM, along with size dimensions and ζ-potentials in aqueous dispersions. Biocompatibility study included tests on haemocompatibility (haemolysis, platelet aggregation, binding to human serum albumin and its esterase activity), antioxidant activity (2,2-diphenyl-1-picrylhydrazyl reaction, NO-radical uptake, Radachlorin photobleaching, photo-induced haemolysis), genotoxicity using DNA comet assay, as well as metabolic activity and proliferation of HEK293 cells.
KW - Biocompatibility
KW - Cytotoxicity
KW - DPPH
KW - Graphene Oxide
KW - HSA
KW - Identification
UR - http://www.scopus.com/inward/record.url?scp=85119935061&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/f62dd625-6471-316c-bfd3-9df7c5e5c1cf/
U2 - 10.1016/j.colsurfb.2021.112232
DO - 10.1016/j.colsurfb.2021.112232
M3 - Article
JO - Colloids and Surfaces B: Biointerfaces
JF - Colloids and Surfaces B: Biointerfaces
SN - 0927-7765
M1 - 112232
ER -
ID: 89392472