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Graphene oxide enriched with oxygen-containing groups: on the way to an increase of antioxidant activity and biocompatibility. / Абделхалим, Абделсаттар Осама Елемам; Мещеряков, Анатолий Анатольевич; Майстренко, Дмитрий Николаевич; Молчанов, Олег Евгеньевич; Агеев, Сергей Вадимович; Иванова, Дарья Андреевна; Ямалова, Наиля Рашитовна; Лутцев, Михаил Денисович; Васина, Любовь Васильевна; Шаройко, Владимир Владимирович; Семёнов, Константин Николаевич.

In: Colloids and Surfaces B: Biointerfaces, 20.11.2021.

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@article{9474bfe321d041d9a96e77dfe3082ae5,
title = "Graphene oxide enriched with oxygen-containing groups: on the way to an increase of antioxidant activity and biocompatibility",
abstract = "The article is dedicated to the comprehensive biocompatibility investigation of synthesised graphene oxide (GO) enriched with oxygen-containing functional groups (⁓85%). GO was synthesised through a modified Hummers and Offeman's method and characterised using 13C NMR, Raman, and IR spectroscopy, XRD, HRTEM, along with size dimensions and ζ-potentials in aqueous dispersions. Biocompatibility study included tests on haemocompatibility (haemolysis, platelet aggregation, binding to human serum albumin and its esterase activity), antioxidant activity (2,2-diphenyl-1-picrylhydrazyl reaction, NO-radical uptake, Radachlorin photobleaching, photo-induced haemolysis), genotoxicity using DNA comet assay, as well as metabolic activity and proliferation of HEK293 cells. ",
keywords = "Biocompatibility, Cytotoxicity, DPPH, Graphene Oxide, HSA, Identification",
author = "Абделхалим, {Абделсаттар Осама Елемам} and Мещеряков, {Анатолий Анатольевич} and Майстренко, {Дмитрий Николаевич} and Молчанов, {Олег Евгеньевич} and Агеев, {Сергей Вадимович} and Иванова, {Дарья Андреевна} and Ямалова, {Наиля Рашитовна} and Лутцев, {Михаил Денисович} and Васина, {Любовь Васильевна} and Шаройко, {Владимир Владимирович} and Семёнов, {Константин Николаевич}",
note = "Publisher Copyright: {\textcopyright} 2021 Elsevier B.V.",
year = "2021",
month = nov,
day = "20",
doi = "10.1016/j.colsurfb.2021.112232",
language = "English",
journal = "Colloids and Surfaces B: Biointerfaces",
issn = "0927-7765",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Graphene oxide enriched with oxygen-containing groups: on the way to an increase of antioxidant activity and biocompatibility

AU - Абделхалим, Абделсаттар Осама Елемам

AU - Мещеряков, Анатолий Анатольевич

AU - Майстренко, Дмитрий Николаевич

AU - Молчанов, Олег Евгеньевич

AU - Агеев, Сергей Вадимович

AU - Иванова, Дарья Андреевна

AU - Ямалова, Наиля Рашитовна

AU - Лутцев, Михаил Денисович

AU - Васина, Любовь Васильевна

AU - Шаройко, Владимир Владимирович

AU - Семёнов, Константин Николаевич

N1 - Publisher Copyright: © 2021 Elsevier B.V.

PY - 2021/11/20

Y1 - 2021/11/20

N2 - The article is dedicated to the comprehensive biocompatibility investigation of synthesised graphene oxide (GO) enriched with oxygen-containing functional groups (⁓85%). GO was synthesised through a modified Hummers and Offeman's method and characterised using 13C NMR, Raman, and IR spectroscopy, XRD, HRTEM, along with size dimensions and ζ-potentials in aqueous dispersions. Biocompatibility study included tests on haemocompatibility (haemolysis, platelet aggregation, binding to human serum albumin and its esterase activity), antioxidant activity (2,2-diphenyl-1-picrylhydrazyl reaction, NO-radical uptake, Radachlorin photobleaching, photo-induced haemolysis), genotoxicity using DNA comet assay, as well as metabolic activity and proliferation of HEK293 cells.

AB - The article is dedicated to the comprehensive biocompatibility investigation of synthesised graphene oxide (GO) enriched with oxygen-containing functional groups (⁓85%). GO was synthesised through a modified Hummers and Offeman's method and characterised using 13C NMR, Raman, and IR spectroscopy, XRD, HRTEM, along with size dimensions and ζ-potentials in aqueous dispersions. Biocompatibility study included tests on haemocompatibility (haemolysis, platelet aggregation, binding to human serum albumin and its esterase activity), antioxidant activity (2,2-diphenyl-1-picrylhydrazyl reaction, NO-radical uptake, Radachlorin photobleaching, photo-induced haemolysis), genotoxicity using DNA comet assay, as well as metabolic activity and proliferation of HEK293 cells.

KW - Biocompatibility

KW - Cytotoxicity

KW - DPPH

KW - Graphene Oxide

KW - HSA

KW - Identification

UR - http://www.scopus.com/inward/record.url?scp=85119935061&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/f62dd625-6471-316c-bfd3-9df7c5e5c1cf/

U2 - 10.1016/j.colsurfb.2021.112232

DO - 10.1016/j.colsurfb.2021.112232

M3 - Article

JO - Colloids and Surfaces B: Biointerfaces

JF - Colloids and Surfaces B: Biointerfaces

SN - 0927-7765

M1 - 112232

ER -

ID: 89392472