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Generation of two iPSC lines (FAMRCi006-A and FAMRCi006-B) from patient with dilated cardiomyopathy and Emery–Dreifuss muscular dystrophy associated with genetic variant LMNAp.Arg527Pro. / Perepelina, Kseniya; Klauzen, Polina; Khudiakov, Aleksandr; Zlotina, Anna; Fomicheva, Yulia; Rudenko, Dmitry; Gordeev, Mikhail; Sergushichev, Alexey; Malashicheva, Anna; Kostareva, Anna.

In: Stem Cell Research, Vol. 43, 101714, 03.2020.

Research output: Contribution to journal › Editorial › peer-review

Harvard

Perepelina, K, Klauzen, P, Khudiakov, A, Zlotina, A, Fomicheva, Y, Rudenko, D, Gordeev, M, Sergushichev, A, Malashicheva, A & Kostareva, A 2020, 'Generation of two iPSC lines (FAMRCi006-A and FAMRCi006-B) from patient with dilated cardiomyopathy and Emery–Dreifuss muscular dystrophy associated with genetic variant LMNAp.Arg527Pro.', Stem Cell Research, vol. 43, 101714. https://doi.org/10.1016/j.scr.2020.101714

APA

Perepelina, K., Klauzen, P., Khudiakov, A., Zlotina, A., Fomicheva, Y., Rudenko, D., Gordeev, M., Sergushichev, A., Malashicheva, A., & Kostareva, A. (2020). Generation of two iPSC lines (FAMRCi006-A and FAMRCi006-B) from patient with dilated cardiomyopathy and Emery–Dreifuss muscular dystrophy associated with genetic variant LMNAp.Arg527Pro. Stem Cell Research, 43, [101714]. https://doi.org/10.1016/j.scr.2020.101714

Vancouver

Perepelina K, Klauzen P, Khudiakov A, Zlotina A, Fomicheva Y, Rudenko D et al. Generation of two iPSC lines (FAMRCi006-A and FAMRCi006-B) from patient with dilated cardiomyopathy and Emery–Dreifuss muscular dystrophy associated with genetic variant LMNAp.Arg527Pro. Stem Cell Research. 2020 Mar;43. 101714. https://doi.org/10.1016/j.scr.2020.101714

Author

Perepelina, Kseniya ; Klauzen, Polina ; Khudiakov, Aleksandr ; Zlotina, Anna ; Fomicheva, Yulia ; Rudenko, Dmitry ; Gordeev, Mikhail ; Sergushichev, Alexey ; Malashicheva, Anna ; Kostareva, Anna. / Generation of two iPSC lines (FAMRCi006-A and FAMRCi006-B) from patient with dilated cardiomyopathy and Emery–Dreifuss muscular dystrophy associated with genetic variant LMNAp.Arg527Pro. In: Stem Cell Research. 2020 ; Vol. 43.

BibTeX

@article{ccf0d4fb09864cca8bedeb01cf6c3563,
title = "Generation of two iPSC lines (FAMRCi006-A and FAMRCi006-B) from patient with dilated cardiomyopathy and Emery–Dreifuss muscular dystrophy associated with genetic variant LMNAp.Arg527Pro.",
abstract = "Mutations in LMNA gene are known to cause a broad range of diseases called laminopathies. We have generated two induced pluripotent stem cell lines FAMRCi006-A and FAMRCi006-B from a patient carrying LMNA p. p.Arg527Pro mutation associated with Emery–Dreifuss muscular dystrophy and dilated cardiomyopathy. Patient-specific peripheral blood mononuclear cells were reprogrammed to iPSCs using Sendai virus reprogramming system. Characterization of iPSCs had revealed pluripotency marker expression, normal karyotype, ability to differentiate into three embryonic germ layers. The reported iPSC lines could be a useful tool for in vitro modeling of laminopathies associated with LMNA genetic variants.",
keywords = "Dilated cardiomyopathy, Emery-Dreifuss muscular dystrophy, Induced pluripotent stem cells, Laminopathies",
author = "Kseniya Perepelina and Polina Klauzen and Aleksandr Khudiakov and Anna Zlotina and Yulia Fomicheva and Dmitry Rudenko and Mikhail Gordeev and Alexey Sergushichev and Anna Malashicheva and Anna Kostareva",
year = "2020",
month = mar,
doi = "10.1016/j.scr.2020.101714",
language = "English",
volume = "43",
journal = "Stem Cell Research",
issn = "1873-5061",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Generation of two iPSC lines (FAMRCi006-A and FAMRCi006-B) from patient with dilated cardiomyopathy and Emery–Dreifuss muscular dystrophy associated with genetic variant LMNAp.Arg527Pro.

AU - Perepelina, Kseniya

AU - Klauzen, Polina

AU - Khudiakov, Aleksandr

AU - Zlotina, Anna

AU - Fomicheva, Yulia

AU - Rudenko, Dmitry

AU - Gordeev, Mikhail

AU - Sergushichev, Alexey

AU - Malashicheva, Anna

AU - Kostareva, Anna

PY - 2020/3

Y1 - 2020/3

N2 - Mutations in LMNA gene are known to cause a broad range of diseases called laminopathies. We have generated two induced pluripotent stem cell lines FAMRCi006-A and FAMRCi006-B from a patient carrying LMNA p. p.Arg527Pro mutation associated with Emery–Dreifuss muscular dystrophy and dilated cardiomyopathy. Patient-specific peripheral blood mononuclear cells were reprogrammed to iPSCs using Sendai virus reprogramming system. Characterization of iPSCs had revealed pluripotency marker expression, normal karyotype, ability to differentiate into three embryonic germ layers. The reported iPSC lines could be a useful tool for in vitro modeling of laminopathies associated with LMNA genetic variants.

AB - Mutations in LMNA gene are known to cause a broad range of diseases called laminopathies. We have generated two induced pluripotent stem cell lines FAMRCi006-A and FAMRCi006-B from a patient carrying LMNA p. p.Arg527Pro mutation associated with Emery–Dreifuss muscular dystrophy and dilated cardiomyopathy. Patient-specific peripheral blood mononuclear cells were reprogrammed to iPSCs using Sendai virus reprogramming system. Characterization of iPSCs had revealed pluripotency marker expression, normal karyotype, ability to differentiate into three embryonic germ layers. The reported iPSC lines could be a useful tool for in vitro modeling of laminopathies associated with LMNA genetic variants.

KW - Dilated cardiomyopathy

KW - Emery-Dreifuss muscular dystrophy

KW - Induced pluripotent stem cells

KW - Laminopathies

UR - http://www.scopus.com/inward/record.url?scp=85079200633&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/ddb548b0-a925-3093-b6dc-adc11445162e/

U2 - 10.1016/j.scr.2020.101714

DO - 10.1016/j.scr.2020.101714

M3 - Editorial

C2 - 32059175

AN - SCOPUS:85079200633

VL - 43

JO - Stem Cell Research

JF - Stem Cell Research

SN - 1873-5061

M1 - 101714

ER -

ID: 53237662