Human iPSC cell line FAMRCi010-A was generated from a patient with restrictive cardiomyopathy carrying FLNC p.Gly2011Arg genetic variant. Patient-specific peripheral blood mononuclear cells were reprogrammed using non-integrative Sendai viruses containing OCT4, SOX2, KLF4, and CMYC. FAMRCi010-A was generated and characterized through the study. The reported iPSC line could be useful tool for in vitro modeling of FLNC-associated cardiomyopathies.

Original languageEnglish
Article number102639
JournalStem Cell Research
Volume59
DOIs
StatePublished - Mar 2022

    Scopus subject areas

  • Developmental Biology
  • Cell Biology

ID: 92247228