Research output: Contribution to journal › Article › peer-review
Testing of an expanded, 800-compound set of analogues of the earlier described Strecker-type alpha-aminonitriles (selected from publicly available Enamine Ltd. Screening Collection) in thermal shift assay against bovine carbonic anhydrase (bCA) led to further validation of this new class of inhibitors and identification a new, refined chemotype represented by inhibitors with 10-improved potency.
| Original language | English |
|---|---|
| Pages (from-to) | 165-171 |
| Number of pages | 7 |
| Journal | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Volume | 35 |
| Issue number | 1 |
| Early online date | 22 Nov 2019 |
| DOIs | |
| State | Published - 1 Jan 2020 |
ID: 49497360