Research output: Contribution to journal › Article › peer-review
Fluorescent Ag-Nanoclusters for Evaluation of Serum Albumin and Immunoglobulin Concentrations in Protein Mixtures. / Mizincev, A. V. ; Sych, T. S. ; Polyanichko, A. M. ; Plotnikova, L. V. ; Garifullin, A. D. ; Voloshin, S. V. ; Kononov, A. I. .
In: Journal of Physics: Conference Series, Vol. 1695, 012061, 2020.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Fluorescent Ag-Nanoclusters for Evaluation of Serum Albumin and Immunoglobulin Concentrations in Protein Mixtures
AU - Mizincev, A. V.
AU - Sych, T. S.
AU - Polyanichko, A. M.
AU - Plotnikova, L. V.
AU - Garifullin, A. D.
AU - Voloshin, S. V.
AU - Kononov, A. I.
PY - 2020
Y1 - 2020
N2 - In this work we designed, synthesized and characterized luminescent metal nanoclusters (NCs) on human serum albumin (HSA) and immunoglobulins (Ig). We demonstrate that the approach developed allows one to determine the relative content of albumins and immunoglobulins in biologically relevant protein mixtures based on the luminescent properties of the NCs. Fast and inexpensive approach which allows to determine concentrations of immunoglobulins (Ig) and serum albumin (HSA) in blood serum might be useful in clinical diagnostics.
AB - In this work we designed, synthesized and characterized luminescent metal nanoclusters (NCs) on human serum albumin (HSA) and immunoglobulins (Ig). We demonstrate that the approach developed allows one to determine the relative content of albumins and immunoglobulins in biologically relevant protein mixtures based on the luminescent properties of the NCs. Fast and inexpensive approach which allows to determine concentrations of immunoglobulins (Ig) and serum albumin (HSA) in blood serum might be useful in clinical diagnostics.
U2 - 10.1088/1742-6596/1695/1/012061
DO - 10.1088/1742-6596/1695/1/012061
M3 - Article
VL - 1695
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
SN - 1742-6588
M1 - 012061
T2 - 7th International School and Conference "Saint-Petersburg OPEN 2020" on Optoelectronics, Photonics, Engineering and Nanostructures
Y2 - 26 April 2020 through 30 April 2020
ER -
ID: 72125575