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FEATURES OF tRNA GENES AND YOUNG SUBFAMILIES Alu-REPEATS EXPRESSION IN PROLIFERATION AND APOPTOSIS. / Kabanov, I. N.; Tishchenko, L. I.

In: Tsitologiia, Vol. 57, No. 5, 01.01.2015, p. 337-344.

Research output: Contribution to journal › Article › peer-review

Harvard

Kabanov, IN & Tishchenko, LI 2015, 'FEATURES OF tRNA GENES AND YOUNG SUBFAMILIES Alu-REPEATS EXPRESSION IN PROLIFERATION AND APOPTOSIS', Tsitologiia, vol. 57, no. 5, pp. 337-344.

APA

Kabanov, I. N., & Tishchenko, L. I. (2015). FEATURES OF tRNA GENES AND YOUNG SUBFAMILIES Alu-REPEATS EXPRESSION IN PROLIFERATION AND APOPTOSIS. Tsitologiia, 57(5), 337-344.

Vancouver

Kabanov IN, Tishchenko LI. FEATURES OF tRNA GENES AND YOUNG SUBFAMILIES Alu-REPEATS EXPRESSION IN PROLIFERATION AND APOPTOSIS. Tsitologiia. 2015 Jan 1;57(5):337-344.

Author

Kabanov, I. N. ; Tishchenko, L. I. / FEATURES OF tRNA GENES AND YOUNG SUBFAMILIES Alu-REPEATS EXPRESSION IN PROLIFERATION AND APOPTOSIS. In: Tsitologiia. 2015 ; Vol. 57, No. 5. pp. 337-344.

BibTeX

@article{31b96bac4b5b4e20a7ca741782734dfd,
title = "FEATURES OF tRNA GENES AND YOUNG SUBFAMILIES Alu-REPEATS EXPRESSION IN PROLIFERATION AND APOPTOSIS",
abstract = "Using human U937 cell culture, we studied the expression of the RNA polymerase III-directeci genes--tRNAi(Met)1, tRNA(His) and Alu-repeats belonging to the youngest subfamilies AluY (AluYa5 and AluYb8) - du- ring camptothecin-induced apoptosis. The level of tRNAiMetl increased 1.5-fold, tRNAHis level did not change, and the level of AluY-RNA increased 4-10-fold after 6 hours of CAM treatment compared to control (non-apoptotic) cells. We also studied the level of AluYb8 DNA methylation at apoptosis U937. We have shown that the level of AluYb8 DNA methylation does not change at different stages of apoptosis, and does not differ in apoptotic and control cells. We assume that the increase in gene expression of young AluY repeats and tRNAi(Met)1 plays a role in the apoptosis pathway realization in the cell.",
author = "Kabanov, {I. N.} and Tishchenko, {L. I.}",
year = "2015",
month = jan,
day = "1",
language = "русский",
volume = "57",
pages = "337--344",
journal = "Цитология",
issn = "0041-3771",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "5",

}

RIS

TY - JOUR

T1 - FEATURES OF tRNA GENES AND YOUNG SUBFAMILIES Alu-REPEATS EXPRESSION IN PROLIFERATION AND APOPTOSIS

AU - Kabanov, I. N.

AU - Tishchenko, L. I.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Using human U937 cell culture, we studied the expression of the RNA polymerase III-directeci genes--tRNAi(Met)1, tRNA(His) and Alu-repeats belonging to the youngest subfamilies AluY (AluYa5 and AluYb8) - du- ring camptothecin-induced apoptosis. The level of tRNAiMetl increased 1.5-fold, tRNAHis level did not change, and the level of AluY-RNA increased 4-10-fold after 6 hours of CAM treatment compared to control (non-apoptotic) cells. We also studied the level of AluYb8 DNA methylation at apoptosis U937. We have shown that the level of AluYb8 DNA methylation does not change at different stages of apoptosis, and does not differ in apoptotic and control cells. We assume that the increase in gene expression of young AluY repeats and tRNAi(Met)1 plays a role in the apoptosis pathway realization in the cell.

AB - Using human U937 cell culture, we studied the expression of the RNA polymerase III-directeci genes--tRNAi(Met)1, tRNA(His) and Alu-repeats belonging to the youngest subfamilies AluY (AluYa5 and AluYb8) - du- ring camptothecin-induced apoptosis. The level of tRNAiMetl increased 1.5-fold, tRNAHis level did not change, and the level of AluY-RNA increased 4-10-fold after 6 hours of CAM treatment compared to control (non-apoptotic) cells. We also studied the level of AluYb8 DNA methylation at apoptosis U937. We have shown that the level of AluYb8 DNA methylation does not change at different stages of apoptosis, and does not differ in apoptotic and control cells. We assume that the increase in gene expression of young AluY repeats and tRNAi(Met)1 plays a role in the apoptosis pathway realization in the cell.

UR - http://www.scopus.com/inward/record.url?scp=84940100985&partnerID=8YFLogxK

M3 - статья

C2 - 26281210

AN - SCOPUS:84940100985

VL - 57

SP - 337

EP - 344

JO - Цитология

JF - Цитология

SN - 0041-3771

IS - 5

ER -

ID: 53110560