Research output: Contribution to journal › Review article › peer-review
Extranuclear functions of nonhistone protein HMGB1. / Chikhirzhina, E. V.; Polyanichko, A. M.; Starkova, T. Yu.
In: Tsitologiya, Vol. 62, No. 10, 2020, p. 716-725.Research output: Contribution to journal › Review article › peer-review
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TY - JOUR
T1 - Extranuclear functions of nonhistone protein HMGB1
AU - Chikhirzhina, E. V.
AU - Polyanichko, A. M.
AU - Starkova, T. Yu
N1 - Publisher Copyright: © 2020 Russian Academy of Sciences. All rights reserved.
PY - 2020
Y1 - 2020
N2 - The non-histone chromosomal protein HMGB1 is one of the most abundant chromatin proteins in eukaryotes. This protein is involved in recombination, transcription, repair and other key processes required for DNA functioning in the cell nucleus. However, HMGB1 can perform a number of other important functions outside the cell nucleus. In this review we describe the mechanisms of protein export from the cell nucleus, as well as the main extranuclear and extracellular functions of HMGB 1.
AB - The non-histone chromosomal protein HMGB1 is one of the most abundant chromatin proteins in eukaryotes. This protein is involved in recombination, transcription, repair and other key processes required for DNA functioning in the cell nucleus. However, HMGB1 can perform a number of other important functions outside the cell nucleus. In this review we describe the mechanisms of protein export from the cell nucleus, as well as the main extranuclear and extracellular functions of HMGB 1.
KW - Alarmin
KW - Cell immune response
KW - Cell metabolism
KW - Cellular senescence
KW - Extranuclear functions of hmgb1
KW - Nonhistone protein hmgb1
UR - http://www.scopus.com/inward/record.url?scp=85094170074&partnerID=8YFLogxK
U2 - 10.31857/S0041377120100016
DO - 10.31857/S0041377120100016
M3 - Review article
AN - SCOPUS:85094170074
VL - 62
SP - 716
EP - 725
JO - Цитология
JF - Цитология
SN - 0041-3771
IS - 10
ER -
ID: 87708636