Early onset of conduct disorder (CD) with callous-unemotional traits has been linked to low levels of dopamine β-hydroxylase (DβH), an enzyme involved in dopamine turnover. The C1021T polymorphism in the DβH gene is a major quantitative-trait locus, regulating the level of DβH. In this study of juvenile delinquents from Northern Russia (n = 180), the polymorphism at -1021 was associated neither with early-onset CD nor with psychopathic traits. Association was found between psychopathic traits and early-onset CD, ADHD and mania.
Original language | English |
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Pages (from-to) | 771-773 |
Number of pages | 3 |
Journal | European Archives of Psychiatry and Clinical Neuroscience |
Volume | 266 |
Issue number | 8 |
DOIs | |
State | Published - 1 Dec 2016 |
ID: 62761159