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Experimental and theoretical study of the transport of silver nanoparticles at their prolonged administration into a mammal organism. / Antsiferova, A. A.; Buzulukov, Yu P.; Kashkarov, P. K.; Kovalchuk, M. V.

In: Crystallography Reports, Vol. 61, No. 6, 01.11.2016, p. 1020-1026.

Research output: Contribution to journal › Article › peer-review

Harvard

Antsiferova, AA, Buzulukov, YP, Kashkarov, PK & Kovalchuk, MV 2016, 'Experimental and theoretical study of the transport of silver nanoparticles at their prolonged administration into a mammal organism', Crystallography Reports, vol. 61, no. 6, pp. 1020-1026. https://doi.org/10.1134/S1063774516060031

APA

Antsiferova, A. A., Buzulukov, Y. P., Kashkarov, P. K., & Kovalchuk, M. V. (2016). Experimental and theoretical study of the transport of silver nanoparticles at their prolonged administration into a mammal organism. Crystallography Reports, 61(6), 1020-1026. https://doi.org/10.1134/S1063774516060031

Vancouver

Antsiferova AA, Buzulukov YP, Kashkarov PK, Kovalchuk MV. Experimental and theoretical study of the transport of silver nanoparticles at their prolonged administration into a mammal organism. Crystallography Reports. 2016 Nov 1;61(6):1020-1026. https://doi.org/10.1134/S1063774516060031

Author

Antsiferova, A. A. ; Buzulukov, Yu P. ; Kashkarov, P. K. ; Kovalchuk, M. V. / Experimental and theoretical study of the transport of silver nanoparticles at their prolonged administration into a mammal organism. In: Crystallography Reports. 2016 ; Vol. 61, No. 6. pp. 1020-1026.

BibTeX

@article{bafa1fde96b349c2906fcfe19de48427,
title = "Experimental and theoretical study of the transport of silver nanoparticles at their prolonged administration into a mammal organism",
abstract = "The transport of silver nanoparticles in the organism of laboratory animals has been investigated. A mathematical model of the biokinetics of prolonged administration of nonmetabolizable and nonaglomerating pharmaceutical preparations is proposed, and its analytical solution is found. Based on the experimental data on the prolonged introduction and excretion of colloidal silver nanoparticles and the numerical approximation of the solutions to the equations for the proposed model, time dependences of the silver mass content in brain and blood are obtained and some other important biokinetic parameters are determined. It is concluded that both chronic1 and subchronic2 peroral application of these nanoparticles as an biologically active additive or antiseptic is potentially dangerous.",
author = "Antsiferova, {A. A.} and Buzulukov, {Yu P.} and Kashkarov, {P. K.} and Kovalchuk, {M. V.}",
note = "Publisher Copyright: {\textcopyright} 2016, Pleiades Publishing, Inc.",
year = "2016",
month = nov,
day = "1",
doi = "10.1134/S1063774516060031",
language = "English",
volume = "61",
pages = "1020--1026",
journal = "Crystallography Reports",
issn = "1063-7745",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "6",

}

RIS

TY - JOUR

T1 - Experimental and theoretical study of the transport of silver nanoparticles at their prolonged administration into a mammal organism

AU - Antsiferova, A. A.

AU - Buzulukov, Yu P.

AU - Kashkarov, P. K.

AU - Kovalchuk, M. V.

N1 - Publisher Copyright: © 2016, Pleiades Publishing, Inc.

PY - 2016/11/1

Y1 - 2016/11/1

N2 - The transport of silver nanoparticles in the organism of laboratory animals has been investigated. A mathematical model of the biokinetics of prolonged administration of nonmetabolizable and nonaglomerating pharmaceutical preparations is proposed, and its analytical solution is found. Based on the experimental data on the prolonged introduction and excretion of colloidal silver nanoparticles and the numerical approximation of the solutions to the equations for the proposed model, time dependences of the silver mass content in brain and blood are obtained and some other important biokinetic parameters are determined. It is concluded that both chronic1 and subchronic2 peroral application of these nanoparticles as an biologically active additive or antiseptic is potentially dangerous.

AB - The transport of silver nanoparticles in the organism of laboratory animals has been investigated. A mathematical model of the biokinetics of prolonged administration of nonmetabolizable and nonaglomerating pharmaceutical preparations is proposed, and its analytical solution is found. Based on the experimental data on the prolonged introduction and excretion of colloidal silver nanoparticles and the numerical approximation of the solutions to the equations for the proposed model, time dependences of the silver mass content in brain and blood are obtained and some other important biokinetic parameters are determined. It is concluded that both chronic1 and subchronic2 peroral application of these nanoparticles as an biologically active additive or antiseptic is potentially dangerous.

UR - http://www.scopus.com/inward/record.url?scp=84995505988&partnerID=8YFLogxK

U2 - 10.1134/S1063774516060031

DO - 10.1134/S1063774516060031

M3 - Article

AN - SCOPUS:84995505988

VL - 61

SP - 1020

EP - 1026

JO - Crystallography Reports

JF - Crystallography Reports

SN - 1063-7745

IS - 6

ER -

ID: 88202746