Exoskeleton gait training with spinal cord neuromodulation

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Exoskeleton gait training with spinal cord neuromodulation. / Ivanenko, Yury; Shapkova, Elena Y.; Petrova, Daria A.; Kleeva, Daria F.; Lebedev, Mikhail A.

In: Frontiers in Human Neuroscience, Vol. 17, 1194702, 11.05.2023.

Research output: Contribution to journal › Review article › peer-review

Author

Ivanenko, Yury ; Shapkova, Elena Y. ; Petrova, Daria A. ; Kleeva, Daria F. ; Lebedev, Mikhail A. / Exoskeleton gait training with spinal cord neuromodulation. In: Frontiers in Human Neuroscience. 2023 ; Vol. 17.

BibTeX

@article{2f354f1b259d443f81dd0d3d9195e35a,

title = "Exoskeleton gait training with spinal cord neuromodulation",

abstract = "Neuromodulating the locomotor network through spinal cord electrical stimulation (SCES) is effective for restoring function in individuals with gait deficits. However, SCES alone has limited effectiveness without concurrent locomotor function training that enhances activity-dependent plasticity of spinal neuronal networks by sensory feedback. This mini review discusses recent developments in using combined interventions, such as SCES added to exoskeleton gait training (EGT). To develop personalized therapies, it is crucial to assess the state of spinal circuitry through a physiologically relevant approach that identifies individual characteristics of spinal cord function to develop person-specific SCES and EGT. The existing literature suggests that combining SCES and EGT to activate the locomotor network can have a synergistic rehabilitative effect on restoring walking abilities, somatic sensation, and cardiovascular and bladder function in paralyzed individuals.",

keywords = "exoskeleton, gait, neuromodulation of spinal networks, neurorehabilitation, spinal cord injury",

author = "Yury Ivanenko and Shapkova, {Elena Y.} and Petrova, {Daria A.} and Kleeva, {Daria F.} and Lebedev, {Mikhail A.}",

year = "2023",

month = may,

day = "11",

doi = "DOI: 10.3389/fnhum.2023.1194702",

language = "English",

volume = "17",

journal = "Frontiers in Human Neuroscience",

issn = "1662-5161",

publisher = "Frontiers Media S.A.",

}

RIS

TY - JOUR

T1 - Exoskeleton gait training with spinal cord neuromodulation

AU - Ivanenko, Yury

AU - Shapkova, Elena Y.

AU - Petrova, Daria A.

AU - Kleeva, Daria F.

AU - Lebedev, Mikhail A.

PY - 2023/5/11

Y1 - 2023/5/11

N2 - Neuromodulating the locomotor network through spinal cord electrical stimulation (SCES) is effective for restoring function in individuals with gait deficits. However, SCES alone has limited effectiveness without concurrent locomotor function training that enhances activity-dependent plasticity of spinal neuronal networks by sensory feedback. This mini review discusses recent developments in using combined interventions, such as SCES added to exoskeleton gait training (EGT). To develop personalized therapies, it is crucial to assess the state of spinal circuitry through a physiologically relevant approach that identifies individual characteristics of spinal cord function to develop person-specific SCES and EGT. The existing literature suggests that combining SCES and EGT to activate the locomotor network can have a synergistic rehabilitative effect on restoring walking abilities, somatic sensation, and cardiovascular and bladder function in paralyzed individuals.

AB - Neuromodulating the locomotor network through spinal cord electrical stimulation (SCES) is effective for restoring function in individuals with gait deficits. However, SCES alone has limited effectiveness without concurrent locomotor function training that enhances activity-dependent plasticity of spinal neuronal networks by sensory feedback. This mini review discusses recent developments in using combined interventions, such as SCES added to exoskeleton gait training (EGT). To develop personalized therapies, it is crucial to assess the state of spinal circuitry through a physiologically relevant approach that identifies individual characteristics of spinal cord function to develop person-specific SCES and EGT. The existing literature suggests that combining SCES and EGT to activate the locomotor network can have a synergistic rehabilitative effect on restoring walking abilities, somatic sensation, and cardiovascular and bladder function in paralyzed individuals.

KW - exoskeleton

KW - gait

KW - neuromodulation of spinal networks

KW - neurorehabilitation

KW - spinal cord injury

UR - https://www.mendeley.com/catalogue/cd8d699b-cb75-3b99-8cc5-6b3a5ce5e9d3/

U2 - DOI: 10.3389/fnhum.2023.1194702

DO - DOI: 10.3389/fnhum.2023.1194702

M3 - Review article

C2 - 37250689

VL - 17

JO - Frontiers in Human Neuroscience

JF - Frontiers in Human Neuroscience

SN - 1662-5161

M1 - 1194702

ER -

ID: 108676599