Research output: Contribution to journal › Article › peer-review
Evaluation of the C60 biodistribution in mice in a micellar ExtraOx form and in an oil solution. / Semenov, Konstantin N.; Ivanova, Daria A.; Ageev, Sergei V.; Petrov, Andrey V.; Podolsky, Nikita E.; Volochaeva, Ekaterina M.; Fedorova, Ekaterina M.; Meshcheriakov, Anatolii A.; Zakharov, Egor E.; Murin, Igor V.; Sharoyko, Vladimir V.
In: Scientific Reports, Vol. 11, No. 1, 8362, 16.04.2021.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Evaluation of the C60 biodistribution in mice in a micellar ExtraOx form and in an oil solution
AU - Semenov, Konstantin N.
AU - Ivanova, Daria A.
AU - Ageev, Sergei V.
AU - Petrov, Andrey V.
AU - Podolsky, Nikita E.
AU - Volochaeva, Ekaterina M.
AU - Fedorova, Ekaterina M.
AU - Meshcheriakov, Anatolii A.
AU - Zakharov, Egor E.
AU - Murin, Igor V.
AU - Sharoyko, Vladimir V.
N1 - Publisher Copyright: © 2021, The Author(s). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/4/16
Y1 - 2021/4/16
N2 - The article is devoted to the study of the pharmacokinetics of fullerene C60 in oil and micellar forms, analysis of its content in blood, liver, lungs, kidneys, heart, brain, adrenal glands, thymus, testicles, and spleen. The highest accumulation of C60 was found in the liver and adrenal glands. As a result of the studies carried out, it was shown that the bioavailability of C60 in the micellar form is higher than that in an oil solution.
AB - The article is devoted to the study of the pharmacokinetics of fullerene C60 in oil and micellar forms, analysis of its content in blood, liver, lungs, kidneys, heart, brain, adrenal glands, thymus, testicles, and spleen. The highest accumulation of C60 was found in the liver and adrenal glands. As a result of the studies carried out, it was shown that the bioavailability of C60 in the micellar form is higher than that in an oil solution.
KW - WATER-SOLUBLE FULLERENE
KW - PHOTOPHYSICAL PROPERTIES
KW - REACTIVE OXYGEN
KW - HIV-1 PROTEASE
KW - OLIVE OIL
KW - IN-VIVO
KW - DERIVATIVES
KW - C60
KW - TOXICITY
KW - SOLVENT
UR - http://www.scopus.com/inward/record.url?scp=85104421741&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/f87ec097-693b-342b-b245-3e0c7ac5cd3c/
U2 - 10.1038/s41598-021-87014-3
DO - 10.1038/s41598-021-87014-3
M3 - Article
C2 - 33863918
AN - SCOPUS:85104421741
VL - 11
JO - Scientific Reports
JF - Scientific Reports
SN - 2045-2322
IS - 1
M1 - 8362
ER -
ID: 77055323