We have applied a 1-D steady-state radiative-convective model with interactive photochemistry to estimate the sensitivity of temperature and ozone mixing ratio to the observed variability of the extraterrestrial spectral solar irradiance. We have carried out several runs using the spectral solar flux for minimum and maximum solar activity conditions. The results show that the ozone and temperature in the stratosphere are mostly sensitive to the solar flux variations in the spectral area between 200 and 220 rim, where they positively correlate with solar flux intensity. In the upper stratosphere and mesosphere the effects of the solar flux variability in the Lyman-alpha line and Schumann-Runge band are found to be very important. The obtained results have an implication for the optimal choice of wavelength to be measured from a satellite and for the understanding of what kind of radiation code should be used in a GCM aimed to study solar-climate connections.