Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review
Epidemiology of Nucleus-Dwelling Holospora: Infection, Transmission, Adaptation, and Interaction with Paramecium. / Schrallhammer, Martina ; Potekhin, Alexey.
Symbiosis: Cellular, Molecular, Medical and Evolutionary Aspects. ed. / Malgorzata Kloc. Springer Nature, 2020. p. 105-135 (Results and Problems in Cell Differentiation; Vol. 69).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review
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TY - CHAP
T1 - Epidemiology of Nucleus-Dwelling Holospora: Infection, Transmission, Adaptation, and Interaction with Paramecium
AU - Schrallhammer, Martina
AU - Potekhin, Alexey
N1 - Publisher Copyright: © 2020, Springer Nature Switzerland AG.
PY - 2020/12
Y1 - 2020/12
N2 - The chapter describes the exceptional symbiotic associations formed between the ciliate Paramecium and Holospora, highly infectious bacteria residing in the host nuclei. Holospora and Holospora-like bacteria (Alphaproteobacteria) are characterized by their ability for vertical and horizontal transmission in host populations, a complex biphasic life cycle, and pronounced preference for host species and colonized cell compartment. These bacteria are obligate intracellular parasites; thus, their metabolic repertoire is dramatically reduced. Nevertheless, they perform complex interactions with the host ciliate. We review ongoing efforts to unravel the molecular adaptations of these bacteria to their unusual lifestyle and the host’s employment in the symbiosis. Furthermore, we summarize current knowledge on the genetic and genomic background of Paramecium–Holospora symbiosis and provide insights into the ecological and evolutionary consequences of this interaction. The diversity and occurrence of symbioses between ciliates and Holospora-like bacteria in nature is discussed in connection with transmission modes of symbionts, host specificity and compatibility of the partners. We aim to summarize 50 years of research devoted to these symbiotic systems and conclude trying to predict some perspectives for further studies.
AB - The chapter describes the exceptional symbiotic associations formed between the ciliate Paramecium and Holospora, highly infectious bacteria residing in the host nuclei. Holospora and Holospora-like bacteria (Alphaproteobacteria) are characterized by their ability for vertical and horizontal transmission in host populations, a complex biphasic life cycle, and pronounced preference for host species and colonized cell compartment. These bacteria are obligate intracellular parasites; thus, their metabolic repertoire is dramatically reduced. Nevertheless, they perform complex interactions with the host ciliate. We review ongoing efforts to unravel the molecular adaptations of these bacteria to their unusual lifestyle and the host’s employment in the symbiosis. Furthermore, we summarize current knowledge on the genetic and genomic background of Paramecium–Holospora symbiosis and provide insights into the ecological and evolutionary consequences of this interaction. The diversity and occurrence of symbioses between ciliates and Holospora-like bacteria in nature is discussed in connection with transmission modes of symbionts, host specificity and compatibility of the partners. We aim to summarize 50 years of research devoted to these symbiotic systems and conclude trying to predict some perspectives for further studies.
UR - http://www.scopus.com/inward/record.url?scp=85097210909&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/b6b0c390-dd8d-3efd-ba0d-231ad987be30/
U2 - 10.1007/978-3-030-51849-3_4
DO - 10.1007/978-3-030-51849-3_4
M3 - Chapter
SN - 978-3-030-51848-6
T3 - Results and Problems in Cell Differentiation
SP - 105
EP - 135
BT - Symbiosis: Cellular, Molecular, Medical and Evolutionary Aspects
A2 - Kloc, Malgorzata
PB - Springer Nature
ER -
ID: 71622303