Research output: Contribution to journal › Article › peer-review
Electrostatic Interactions in the Formation of DNA Complexes with Cis- and Trans-Isomers of Azobenzene-Containing Surfactants in Solutions with Di- and Trivalent Metal Ions. / Касьяненко, Нина Анатольевна; Силантьева, Ирина Александровна; Габрусёнок, Павел Владимирович; Santer, Svetlana; Комолкин, Андрей Владимирович.
In: ACS Omega, Vol. 8, No. 16, 25.04.2023, p. 14597-14609.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Electrostatic Interactions in the Formation of DNA Complexes with Cis- and Trans-Isomers of Azobenzene-Containing Surfactants in Solutions with Di- and Trivalent Metal Ions
AU - Касьяненко, Нина Анатольевна
AU - Силантьева, Ирина Александровна
AU - Габрусёнок, Павел Владимирович
AU - Santer, Svetlana
AU - Комолкин, Андрей Владимирович
PY - 2023/4/25
Y1 - 2023/4/25
N2 - The effect of the presence of divalent and trivalent metal ions in solutions upon DNA packaging induced by the photosensitive azobenzene-containing surfactant is considered. It has been shown that the addition of divalent and trivalent metal ions does not affect the DNA-surfactant interaction for both the cis- and the trans-isomers of the surfactant. At the same time, the ionic strength of the solution, which is provided by a certain concentration of the salt, has a huge impact. It affects the association of surfactant molecules with each other and their binding to DNA. It has been shown by computer simulation that cobalt hexamine is attracted to the N7 atom of guanine in the major groove of DNA and does not penetrate into grooves near the AT base pairs.
AB - The effect of the presence of divalent and trivalent metal ions in solutions upon DNA packaging induced by the photosensitive azobenzene-containing surfactant is considered. It has been shown that the addition of divalent and trivalent metal ions does not affect the DNA-surfactant interaction for both the cis- and the trans-isomers of the surfactant. At the same time, the ionic strength of the solution, which is provided by a certain concentration of the salt, has a huge impact. It affects the association of surfactant molecules with each other and their binding to DNA. It has been shown by computer simulation that cobalt hexamine is attracted to the N7 atom of guanine in the major groove of DNA and does not penetrate into grooves near the AT base pairs.
UR - https://www.mendeley.com/catalogue/0b61144f-a65c-3323-81fb-df7b3b1f9eb8/
U2 - 10.1021/acsomega.3c00419
DO - 10.1021/acsomega.3c00419
M3 - Article
C2 - 37125131
VL - 8
SP - 14597
EP - 14609
JO - ACS Omega
JF - ACS Omega
SN - 2470-1343
IS - 16
ER -
ID: 104813904