DOI

A new coronavirus disease (COVID-19) has already affected millions of people in 213 countries. The possibilities of treatment have been reviewed in recent publications but there are many controversial results and conclusions. An analysis of the studies did not reveal a difference in mortality level between people treated with standard therapy, such as antiviral drugs and dexamethasone, and new antiviral drugs/additional immune therapy. However, most studies describe clinical improvement and a decrease in mortality among patients with severe and critical conditions, with the early initiation of additional immune therapy. Possible new targets based on viral life cycles were considered. Unfortunately, the data analysis on the efficacy of different medicine and therapy regimens among patients with COVID-19, showed little success in decreasing the mortality rate in all treatment methods. Some efficacy has been shown with an immunosuppressive therapy in small patient samples, but when a larger number of patients were analyzed the data did not differ significantly from the control groups.
Original languageEnglish
Article number753
Number of pages16
JournalLife
Volume11
Issue number8
DOIs
StatePublished - Aug 2021

    Research areas

  • coronavirus infection, Sars-coV-2, COVID-19, antiviral therapy, immune therapy, Cytokines, plasma, intravenous immunoglobulin IgG, Plasma, Antiviral therapy, Coronavirus infection, Intravenous immunoglobulin IgG, SARS-CoV-2, Immune therapy, CELLS, MULTICENTER, PROTEIN, SARS CORONAVIRUS, cytokines, CONVALESCENT PLASMA, EXPRESSION

    Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Biochemistry, Genetics and Molecular Biology(all)
  • Paleontology
  • Space and Planetary Science

ID: 85023289