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Effect of sodium hypochlorite on nucleic acids of different primary and secondary structures. / Osinnikova, D. N.; Moroshkina, E. B.; Mokronosova, E. S.

In: Journal of Physics: Conference Series, Vol. 1400, No. 3, 033001, 11.12.2019.

Research output: Contribution to journal › Conference article › peer-review

Harvard

Osinnikova, DN, Moroshkina, EB & Mokronosova, ES 2019, 'Effect of sodium hypochlorite on nucleic acids of different primary and secondary structures', Journal of Physics: Conference Series, vol. 1400, no. 3, 033001. https://doi.org/10.1088/1742-6596/1400/3/033001

APA

Osinnikova, D. N., Moroshkina, E. B., & Mokronosova, E. S. (2019). Effect of sodium hypochlorite on nucleic acids of different primary and secondary structures. Journal of Physics: Conference Series, 1400(3), [033001]. https://doi.org/10.1088/1742-6596/1400/3/033001

Vancouver

Osinnikova DN, Moroshkina EB, Mokronosova ES. Effect of sodium hypochlorite on nucleic acids of different primary and secondary structures. Journal of Physics: Conference Series. 2019 Dec 11;1400(3). 033001. https://doi.org/10.1088/1742-6596/1400/3/033001

Author

Osinnikova, D. N. ; Moroshkina, E. B. ; Mokronosova, E. S. / Effect of sodium hypochlorite on nucleic acids of different primary and secondary structures. In: Journal of Physics: Conference Series. 2019 ; Vol. 1400, No. 3.

BibTeX

@article{fe2dd5253b624ae6ab30a2e105004d21,
title = "Effect of sodium hypochlorite on nucleic acids of different primary and secondary structures",
abstract = "The effect of sodium hypochlorite (NaClO) on nucleic acids (NAs) was investigated. The effect of biomolecular structure on resistance to hypochlorite was analysed: Plasmid bacterial DNA, calf thymus DNA, synthetic polyadenylic-uridic acid samples were studied, as well as individual nucleotides (adenosine-5'-tetraphosphoric acid and guanosin-2', 3-cyclophosphoric acid). The effect of sodium hypochlorite on DNA was investigated depending on the concentrations of the components. We have also performed detailed analysis of the kinetics of the reaction between the NAs and NaClO. It was found that both the destruction of the secondary structure of DNA (denaturation) and the chemical modification of nitrogenous bases, presumably chlorination, occur. Presence of a stable double-stranded structure of DNA slows down the chemical reaction of sodium hypochlorite with nitrogenous bases of DNA.",
keywords = "Chemical modification, Chlorine compounds, Hydrometallurgy, Reaction kinetics, sodium, Sodium compounds",
author = "Osinnikova, {D. N.} and Moroshkina, {E. B.} and Mokronosova, {E. S.}",
year = "2019",
month = dec,
day = "11",
doi = "10.1088/1742-6596/1400/3/033001",
language = "English",
volume = "1400",
journal = "Journal of Physics: Conference Series",
issn = "1742-6588",
publisher = "IOP Publishing Ltd.",
number = "3",
note = "International Conference PhysicA.SPb 2019 ; Conference date: 22-10-2019 Through 24-10-2019",

}

RIS

TY - JOUR

T1 - Effect of sodium hypochlorite on nucleic acids of different primary and secondary structures

AU - Osinnikova, D. N.

AU - Moroshkina, E. B.

AU - Mokronosova, E. S.

PY - 2019/12/11

Y1 - 2019/12/11

N2 - The effect of sodium hypochlorite (NaClO) on nucleic acids (NAs) was investigated. The effect of biomolecular structure on resistance to hypochlorite was analysed: Plasmid bacterial DNA, calf thymus DNA, synthetic polyadenylic-uridic acid samples were studied, as well as individual nucleotides (adenosine-5'-tetraphosphoric acid and guanosin-2', 3-cyclophosphoric acid). The effect of sodium hypochlorite on DNA was investigated depending on the concentrations of the components. We have also performed detailed analysis of the kinetics of the reaction between the NAs and NaClO. It was found that both the destruction of the secondary structure of DNA (denaturation) and the chemical modification of nitrogenous bases, presumably chlorination, occur. Presence of a stable double-stranded structure of DNA slows down the chemical reaction of sodium hypochlorite with nitrogenous bases of DNA.

AB - The effect of sodium hypochlorite (NaClO) on nucleic acids (NAs) was investigated. The effect of biomolecular structure on resistance to hypochlorite was analysed: Plasmid bacterial DNA, calf thymus DNA, synthetic polyadenylic-uridic acid samples were studied, as well as individual nucleotides (adenosine-5'-tetraphosphoric acid and guanosin-2', 3-cyclophosphoric acid). The effect of sodium hypochlorite on DNA was investigated depending on the concentrations of the components. We have also performed detailed analysis of the kinetics of the reaction between the NAs and NaClO. It was found that both the destruction of the secondary structure of DNA (denaturation) and the chemical modification of nitrogenous bases, presumably chlorination, occur. Presence of a stable double-stranded structure of DNA slows down the chemical reaction of sodium hypochlorite with nitrogenous bases of DNA.

KW - Chemical modification

KW - Chlorine compounds

KW - Hydrometallurgy

KW - Reaction kinetics

KW - sodium

KW - Sodium compounds

UR - http://www.scopus.com/inward/record.url?scp=85077639484&partnerID=8YFLogxK

U2 - 10.1088/1742-6596/1400/3/033001

DO - 10.1088/1742-6596/1400/3/033001

M3 - Conference article

AN - SCOPUS:85077639484

VL - 1400

JO - Journal of Physics: Conference Series

JF - Journal of Physics: Conference Series

SN - 1742-6588

IS - 3

M1 - 033001

T2 - International Conference PhysicA.SPb 2019

Y2 - 22 October 2019 through 24 October 2019

ER -

ID: 51895718