Research output: Contribution to journal › Article › peer-review
Effect of dimethyl sulfoxide on DNA conformation in solution. / Kosmotynskaya, Yu V.; Bogdanov, A. A.; Kas'yanenko, N. A.
In: Russian Journal of Physical Chemistry A, Vol. 79, No. SUPPL.1, 2005, p. S86-S89.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Effect of dimethyl sulfoxide on DNA conformation in solution
AU - Kosmotynskaya, Yu V.
AU - Bogdanov, A. A.
AU - Kas'yanenko, N. A.
N1 - Copyright: Copyright 2009 Elsevier B.V., All rights reserved.
PY - 2005
Y1 - 2005
N2 - DNA conformations in aqueous solutions containing various dimethyl sulfoxide (DMSO) concentrations were studied. Small (to 7 vol %) DMSO concentrations do not affect the spectroscopic characteristics, volume, or persistent length of a DNA molecule. Higher DMSO concentrations alter the circular dichroism (CD) spectra of the DNA. The optical anisotropy of the macromolecule changes, and the coil volume decreases, but the double-helix DNA structure is not noticeably perturbed. DMSO effects on native and denatured DNA are compared. A
AB - DNA conformations in aqueous solutions containing various dimethyl sulfoxide (DMSO) concentrations were studied. Small (to 7 vol %) DMSO concentrations do not affect the spectroscopic characteristics, volume, or persistent length of a DNA molecule. Higher DMSO concentrations alter the circular dichroism (CD) spectra of the DNA. The optical anisotropy of the macromolecule changes, and the coil volume decreases, but the double-helix DNA structure is not noticeably perturbed. DMSO effects on native and denatured DNA are compared. A
UR - http://www.scopus.com/inward/record.url?scp=28444468085&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:28444468085
VL - 79
SP - S86-S89
JO - Russian Journal of Physical Chemistry A
JF - Russian Journal of Physical Chemistry A
SN - 0036-0244
IS - SUPPL.1
ER -
ID: 73391392