Research output: Contribution to journal › Article
Effect of crystallization conditions on polymorphic diversity of malic acid RS-racemate. / Isakov, A.I.; Kotelnikova, E.N.; Kryuchkova, L.Y.; Lorenz, H.
In: Transactions of Tianjin University, Vol. 19, No. 2, 2013, p. 86-91.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Effect of crystallization conditions on polymorphic diversity of malic acid RS-racemate
AU - Isakov, A.I.
AU - Kotelnikova, E.N.
AU - Kryuchkova, L.Y.
AU - Lorenz, H.
PY - 2013
Y1 - 2013
N2 - Enantiomers (R(+) and S(−)), RS-racemate (double compound) and (R+S)-conglomerate (mechanical mixture of enantiomers) of malic acid C4H6O5 have been investigated by means of X-ray diffractometry and high temperature X-ray diffraction method. The RS-racemate was found to be able to form three polymorphic modifications, which we denominated as M1 (monoclinic, space group P21/c), M2 (monoclinic, space group Cc), and Tc (triclinic, space group P-1), the latter modification having been unknown before. Modification Tc was also described, and its Xray diffraction characteristics, including interplanar spacings d, hkl indices, unit cell parameters, were defined. In addition, X-ray diffraction characteristics for both reported earlier M1 and M2 monoclinic polymorphic modifications were measured with higher accuracy. The ability of RS-racemate to form one of the above three modifications (M1, M2, and Tc) or their mixtures containing various proportions and combinations of the components (M1+M2, M1+Tc, or M2 +Tc) was fo
AB - Enantiomers (R(+) and S(−)), RS-racemate (double compound) and (R+S)-conglomerate (mechanical mixture of enantiomers) of malic acid C4H6O5 have been investigated by means of X-ray diffractometry and high temperature X-ray diffraction method. The RS-racemate was found to be able to form three polymorphic modifications, which we denominated as M1 (monoclinic, space group P21/c), M2 (monoclinic, space group Cc), and Tc (triclinic, space group P-1), the latter modification having been unknown before. Modification Tc was also described, and its Xray diffraction characteristics, including interplanar spacings d, hkl indices, unit cell parameters, were defined. In addition, X-ray diffraction characteristics for both reported earlier M1 and M2 monoclinic polymorphic modifications were measured with higher accuracy. The ability of RS-racemate to form one of the above three modifications (M1, M2, and Tc) or their mixtures containing various proportions and combinations of the components (M1+M2, M1+Tc, or M2 +Tc) was fo
KW - polymorphism
KW - racemic
KW - chiral
U2 - 10.1007/s12209-013-1820-3
DO - 10.1007/s12209-013-1820-3
M3 - Article
VL - 19
SP - 86
EP - 91
JO - Transactions of Tianjin University
JF - Transactions of Tianjin University
SN - 1006-4982
IS - 2
ER -
ID: 7389121