Research output: Contribution to journal › Conference article
Effect of Ca2+ and Mn2+ Ions on Formation of Structurally Ordered Nanoscale Complexes of DNA with Nuclear Proteins HMGB1 and H1. / Chikhirzhina, E. V. ; Osinnikova, D. N. ; Polyanichko, A. M. .
In: Journal of Physics: Conference Series, Vol. 1695, 2020, p. 169-170.Research output: Contribution to journal › Conference article
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TY - JOUR
T1 - Effect of Ca2+ and Mn2+ Ions on Formation of Structurally Ordered Nanoscale Complexes of DNA with Nuclear Proteins HMGB1 and H1
AU - Chikhirzhina, E. V.
AU - Osinnikova, D. N.
AU - Polyanichko, A. M.
PY - 2020
Y1 - 2020
N2 - The structural organization of DNA in complex with linker histone H1 and non-histone chromosomal protein HMGB1 in presence of calcium and manganese ions have been studied using FTIR and UV circular dichroism spectroscopy. We have demonstrated that the presence of calcium ions leads to the formation of highly ordered DNA-H1-HMGB1 structures, while manganese ions decrease the order in the earlier reported nanoscale complexes.
AB - The structural organization of DNA in complex with linker histone H1 and non-histone chromosomal protein HMGB1 in presence of calcium and manganese ions have been studied using FTIR and UV circular dichroism spectroscopy. We have demonstrated that the presence of calcium ions leads to the formation of highly ordered DNA-H1-HMGB1 structures, while manganese ions decrease the order in the earlier reported nanoscale complexes.
UR - https://iopscience.iop.org/article/10.1088/1742-6596/1695/1/012059/meta
M3 - Conference article
VL - 1695
SP - 169
EP - 170
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
SN - 1742-6588
T2 - 7th International School and Conference "Saint-Petersburg OPEN 2020" on Optoelectronics, Photonics, Engineering and Nanostructures
Y2 - 26 April 2020 through 30 April 2020
ER -
ID: 85579120