Dynamics of structural parameters and accumulation of collagen fibrils in rat lung after inhalations of surfactant-BL at various terms of bleomycin-induced alveolitis. / Volchkov, V. A.; Dubrovskaya, V. F.; Valkovich, A. A.; Klestova, O. V.; Serzhanina, V. A.; Zhuikov, A. G.; Seiliev, A. A.; Rosenberg, O. A.
In: Bulletin of Experimental Biology and Medicine, Vol. 161, No. 4, 08.2016, p. 465-467.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Dynamics of structural parameters and accumulation of collagen fibrils in rat lung after inhalations of surfactant-BL at various terms of bleomycin-induced alveolitis
AU - Volchkov, V. A.
AU - Dubrovskaya, V. F.
AU - Valkovich, A. A.
AU - Klestova, O. V.
AU - Serzhanina, V. A.
AU - Zhuikov, A. G.
AU - Seiliev, A. A.
AU - Rosenberg, O. A.
N1 - Publisher Copyright: © 2016 Springer Science+Business Media New York.
PY - 2016/8
Y1 - 2016/8
N2 - Rats were subjected to surfactant-BL inhalations at the early and late phases of bleomycininduced alveolitis. In both regimens, the drug reduced the severity of inflammation. In the acute phase of alveolitis, the therapeutic effect of inhalation was accompanied by activation of the synthesis of fine lose collagen fibrils. In the late phase of alveolitis, inhalation of surfactant-BL thickened the fibrils and diminished their population in alveolar walls.
AB - Rats were subjected to surfactant-BL inhalations at the early and late phases of bleomycininduced alveolitis. In both regimens, the drug reduced the severity of inflammation. In the acute phase of alveolitis, the therapeutic effect of inhalation was accompanied by activation of the synthesis of fine lose collagen fibrils. In the late phase of alveolitis, inhalation of surfactant-BL thickened the fibrils and diminished their population in alveolar walls.
KW - Bleomycin
KW - Collagen fibrils
KW - Lung
KW - Rats
KW - Surfactant-BL
UR - http://www.scopus.com/inward/record.url?scp=85007000864&partnerID=8YFLogxK
U2 - 10.1007/s10517-016-3439-6
DO - 10.1007/s10517-016-3439-6
M3 - Article
C2 - 27591866
AN - SCOPUS:85007000864
VL - 161
SP - 465
EP - 467
JO - Bulletin of Experimental Biology and Medicine
JF - Bulletin of Experimental Biology and Medicine
SN - 0007-4888
IS - 4
ER -
ID: 85029420