Dynamics of 5-Aminolevulinic Acid-Induced Accumulation of Protoporphyrin IX in Three Cell Lines of Different Origin

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Dynamics of 5-Aminolevulinic Acid-Induced Accumulation of Protoporphyrin IX in Three Cell Lines of Different Origin. / Gorbenko, D. A.; Belashov, A. V.; Belyaeva, T. N.; Kornilova, E. S.; Litvinov, I. K.; Semenova, I. V.; Vasyutinskii, O. S.

In: Technical Physics, Vol. 66, No. 1, 01.2021, p. 145-148.

Research output: Contribution to journal › Article › peer-review

Author

Gorbenko, D. A. ; Belashov, A. V. ; Belyaeva, T. N. ; Kornilova, E. S. ; Litvinov, I. K. ; Semenova, I. V. ; Vasyutinskii, O. S. / Dynamics of 5-Aminolevulinic Acid-Induced Accumulation of Protoporphyrin IX in Three Cell Lines of Different Origin. In: Technical Physics. 2021 ; Vol. 66, No. 1. pp. 145-148.

BibTeX

@article{e969814ec1ef45bd925a1480a5240abb,

title = "Dynamics of 5-Aminolevulinic Acid-Induced Accumulation of Protoporphyrin IX in Three Cell Lines of Different Origin",

abstract = "The dynamics of synthesis and accumulation of protoporphyrin IX induced by 5-aminolevulinic acid (5-ALA) was studied using confocal fluorescence microscopy in three established cell lines: immortalized cells originated from human tumor tissues-epithelial carcinoma (HeLa cells) and lung adenocarcinoma (A549 cells)-and immortalized fibroblast-like mouse embryo cells (3T3 line). The accumulation of protoporphyrin IX in cell cultures was estimated by analyzing the intensity of its fluorescence. The dynamics of changes in the fluorescence intensity with the cell incubation duration in the presence of 5-ALA and with the 5-ALA concentration was studied.",

author = "Gorbenko, {D. A.} and Belashov, {A. V.} and Belyaeva, {T. N.} and Kornilova, {E. S.} and Litvinov, {I. K.} and Semenova, {I. V.} and Vasyutinskii, {O. S.}",

year = "2021",

month = jan,

doi = "10.1134/s1063784221010084",

language = "English",

volume = "66",

pages = "145--148",

journal = "Technical Physics",

issn = "1063-7842",

publisher = "Pleiades Publishing",

number = "1",

}

RIS

TY - JOUR

T1 - Dynamics of 5-Aminolevulinic Acid-Induced Accumulation of Protoporphyrin IX in Three Cell Lines of Different Origin

AU - Gorbenko, D. A.

AU - Belashov, A. V.

AU - Belyaeva, T. N.

AU - Kornilova, E. S.

AU - Litvinov, I. K.

AU - Semenova, I. V.

AU - Vasyutinskii, O. S.

PY - 2021/1

Y1 - 2021/1

N2 - The dynamics of synthesis and accumulation of protoporphyrin IX induced by 5-aminolevulinic acid (5-ALA) was studied using confocal fluorescence microscopy in three established cell lines: immortalized cells originated from human tumor tissues-epithelial carcinoma (HeLa cells) and lung adenocarcinoma (A549 cells)-and immortalized fibroblast-like mouse embryo cells (3T3 line). The accumulation of protoporphyrin IX in cell cultures was estimated by analyzing the intensity of its fluorescence. The dynamics of changes in the fluorescence intensity with the cell incubation duration in the presence of 5-ALA and with the 5-ALA concentration was studied.

AB - The dynamics of synthesis and accumulation of protoporphyrin IX induced by 5-aminolevulinic acid (5-ALA) was studied using confocal fluorescence microscopy in three established cell lines: immortalized cells originated from human tumor tissues-epithelial carcinoma (HeLa cells) and lung adenocarcinoma (A549 cells)-and immortalized fibroblast-like mouse embryo cells (3T3 line). The accumulation of protoporphyrin IX in cell cultures was estimated by analyzing the intensity of its fluorescence. The dynamics of changes in the fluorescence intensity with the cell incubation duration in the presence of 5-ALA and with the 5-ALA concentration was studied.

UR - http://www.scopus.com/inward/record.url?scp=85101866863&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/26ec0ee2-3647-3df5-92a6-25bbbf632317/

U2 - 10.1134/s1063784221010084

DO - 10.1134/s1063784221010084

M3 - Article

AN - SCOPUS:85101866863

VL - 66

SP - 145

EP - 148

JO - Technical Physics

JF - Technical Physics

SN - 1063-7842

IS - 1

ER -

ID: 76655949