Research output: Contribution to journal › Article › peer-review
Dynamic surface properties of DNA/surfactant solutions : Impact of DNA structure. / Lyadinskaya, Vanda V.; Tseng, Wen-Chi; Lin, Shi-Yow; Noskov, Boris A.
In: Journal of the Taiwan Institute of Chemical Engineers, Vol. 68, 11.2016, p. 59-63.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Dynamic surface properties of DNA/surfactant solutions
T2 - Impact of DNA structure
AU - Lyadinskaya, Vanda V.
AU - Tseng, Wen-Chi
AU - Lin, Shi-Yow
AU - Noskov, Boris A.
PY - 2016/11
Y1 - 2016/11
N2 - The dynamic surface properties of mixed solutions of a cationic surfactant - cetyltrimethylammonium bromide (CTAB) - and different types of deoxyribonucleic acid in both linear (ctDNA) and plasmid (pDNA) forms were studied by surface tensiometry and dilational surface rheology. The dynamic surface elasticity and the dynamic surface tension depended strongly on the DNA type. The adsorption layers of ctDNA/CTAB solutions exhibited strong elastic behavior in a wide range of surfactant concentrations. Contrariwise, the addition of plasmid DNA altered the dynamic surface elasticity of CTAB solutions only slightly. The significant difference in the size of macromolecules, their conformation, and, thereby, their effective charge leads to the formation of DNA/CTAB complexes of different surface activity and causes drastic changes in the rheology of the adsorption layer. (C) 2016 Taiwan Institute of Chemical Engineers. Published by Elsevier B.V. All rights reserved.
AB - The dynamic surface properties of mixed solutions of a cationic surfactant - cetyltrimethylammonium bromide (CTAB) - and different types of deoxyribonucleic acid in both linear (ctDNA) and plasmid (pDNA) forms were studied by surface tensiometry and dilational surface rheology. The dynamic surface elasticity and the dynamic surface tension depended strongly on the DNA type. The adsorption layers of ctDNA/CTAB solutions exhibited strong elastic behavior in a wide range of surfactant concentrations. Contrariwise, the addition of plasmid DNA altered the dynamic surface elasticity of CTAB solutions only slightly. The significant difference in the size of macromolecules, their conformation, and, thereby, their effective charge leads to the formation of DNA/CTAB complexes of different surface activity and causes drastic changes in the rheology of the adsorption layer. (C) 2016 Taiwan Institute of Chemical Engineers. Published by Elsevier B.V. All rights reserved.
KW - Dilational surface rheology
KW - Plasmid DNA
KW - Calf thymus DNA
KW - DNA/surfactant complexes
KW - Adsorption kinetics
KW - Surface tension
KW - PLASMID DNA
KW - CATIONIC SURFACTANT
KW - AIR/WATER INTERFACE
KW - GENE DELIVERY
KW - COMPLEXES
KW - BROMIDE
KW - MOLECULES
KW - MIXTURES
KW - LANGMUIR
KW - TENSION
U2 - 10.1016/j.jtice.2016.09.016
DO - 10.1016/j.jtice.2016.09.016
M3 - статья
VL - 68
SP - 59
EP - 63
JO - Journal of the Taiwan Institute of Chemical Engineers
JF - Journal of the Taiwan Institute of Chemical Engineers
SN - 1876-1070
ER -
ID: 7591672