Dual use of propargylamine building blocks in the construction of polyheterocyclic scaffolds

Research output: Contribution to journal › Article › peer-review

DOI

https://doi.org/10.1016/j.tetlet.2020.151970
Final published version

Anna Bakholdina
Alexei Lukin
Olga Bakulina
Natalia Guranova
Mikhail Krasavin

The cyclization reactions of 2-(N-propargyl)imidazole-2-yl)indoles (synthesized via the hydroamination reaction between N-propargyl indole-2-carboxamides and propargylamine) have been investigated under Lewis acid- and base-promoted conditions. The polyheterocyclic compounds thus obtained were shown to possess promising photophysical properties.

Original language	English
Article number	151970
Number of pages	4
Journal	Tetrahedron Letters
Volume	61
Issue number	24
Early online date	23 Apr 2020
DOIs	https://doi.org/10.1016/j.tetlet.2020.151970
State	Published - 11 Jun 2020

Scopus subject areas

Drug Discovery
Biochemistry
Organic Chemistry

Research areas

Blue emitters, Cesium carbonate, Hydroamination-cyclization, Polyheterocycles, Propargyl group cyclization, Zinc triflate, HYDROAMINATION, ALKYNES, EFFICIENT

ID: 53180789