DOI

The purpose of this work is to compare DNA condensation induced by small multivalent ions and polycations. DNA complexes with trivalent ions Fe 3+, La3+, [Co(NH3)6]3+, spermidine and cationic polymers in a solution were investigated. The influence of cations on the volume, persistent length, and secondary structure of DNA was studied. A comparison of DNA packaging induced by trivalent ions and polycations was made. DNA complexes with trivalent metal ions and polycations were characterized by means of low gradient viscometry, dynamic light scattering, circular dichroism, UV spectrometry, flow birefringence, and atomic force microscopy.

Original languageEnglish
Title of host publicationNanomaterials for Application in Medicine and Biology
EditorsM Giersig, GB Khomutov
PublisherSpringer Nature
Pages29-38
Number of pages10
ISBN (Print)9781402068270
DOIs
StatePublished - 2008
EventNATO Advanced Research Workshop on Nanomaterials for Applications in Medicine and Biology - Bonn, Germany
Duration: 4 Oct 2006 → 6 Oct 2006

Publication series

NameNATO Science for Peace and Security Series B: Physics and Biophysics
ISSN (Print)1874-6500

Conference

ConferenceNATO Advanced Research Workshop on Nanomaterials for Applications in Medicine and Biology
Country/TerritoryGermany
CityBonn
Period4/10/06 → 6/10/06

    Scopus subject areas

  • Biotechnology
  • Biophysics
  • Physics and Astronomy(all)
  • Electrical and Electronic Engineering

    Research areas

  • Cobalt hexamine, DNA condensation, DNA-polymer complexes, Trivalent metal ions

ID: 73390157