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Distribution of structural polymorphisms of angiotensin converting enzyme and serotonin receptor (5-HT2A) genes among long-living individuals from Northwestern Russia. / Smirnova, T.Y.; Spivak, D.L.; Yakupova, G.S.; Zakharchuk, A.G.; Spivak, I.M.

In: Advances in Gerontology (Uspekhi Gerontologii), Vol. 2, No. 3, 2012, p. 247-252.

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Smirnova, T.Y. ; Spivak, D.L. ; Yakupova, G.S. ; Zakharchuk, A.G. ; Spivak, I.M. / Distribution of structural polymorphisms of angiotensin converting enzyme and serotonin receptor (5-HT2A) genes among long-living individuals from Northwestern Russia. In: Advances in Gerontology (Uspekhi Gerontologii). 2012 ; Vol. 2, No. 3. pp. 247-252.

BibTeX

@article{4e74ab018a884dc29d46ef015d4a0824,
title = "Distribution of structural polymorphisms of angiotensin converting enzyme and serotonin receptor (5-HT2A) genes among long-living individuals from Northwestern Russia",
abstract = "The I/D polymorphism of the angiotensin converting enzyme (ACE) gene and C102T polymorphism of the serotonin receptor gene (5-HT2A) were studied in a group of long-living individuals from northwestern Russia. No significant differences in allele frequencies of these genes were detected between long-living individuals and young people. At the same time, strongly pronounced differences in the 5-HT2A gene A1 and A2 alleles in populations of the northwestern region of the Russian Federation and the United States (0.397 (A1) and 0.603 (A2), and 0.615 (A1) and 0.385 (A2), respectively) were detected. These significant population differences deserve serious attention and a detailed analysis of polymorphism in other serotonin system genes in different populations of Russian Federation. {\textcopyright} Pleiades Publishing, Ltd., 2012.",
author = "T.Y. Smirnova and D.L. Spivak and G.S. Yakupova and A.G. Zakharchuk and I.M. Spivak",
year = "2012",
doi = "10.1134/S2079057012030149",
language = "English",
volume = "2",
pages = "247--252",
journal = "Advances in Gerontology",
issn = "2079-0570",
publisher = "Springer Nature",
number = "3",

}

RIS

TY - JOUR

T1 - Distribution of structural polymorphisms of angiotensin converting enzyme and serotonin receptor (5-HT2A) genes among long-living individuals from Northwestern Russia

AU - Smirnova, T.Y.

AU - Spivak, D.L.

AU - Yakupova, G.S.

AU - Zakharchuk, A.G.

AU - Spivak, I.M.

PY - 2012

Y1 - 2012

N2 - The I/D polymorphism of the angiotensin converting enzyme (ACE) gene and C102T polymorphism of the serotonin receptor gene (5-HT2A) were studied in a group of long-living individuals from northwestern Russia. No significant differences in allele frequencies of these genes were detected between long-living individuals and young people. At the same time, strongly pronounced differences in the 5-HT2A gene A1 and A2 alleles in populations of the northwestern region of the Russian Federation and the United States (0.397 (A1) and 0.603 (A2), and 0.615 (A1) and 0.385 (A2), respectively) were detected. These significant population differences deserve serious attention and a detailed analysis of polymorphism in other serotonin system genes in different populations of Russian Federation. © Pleiades Publishing, Ltd., 2012.

AB - The I/D polymorphism of the angiotensin converting enzyme (ACE) gene and C102T polymorphism of the serotonin receptor gene (5-HT2A) were studied in a group of long-living individuals from northwestern Russia. No significant differences in allele frequencies of these genes were detected between long-living individuals and young people. At the same time, strongly pronounced differences in the 5-HT2A gene A1 and A2 alleles in populations of the northwestern region of the Russian Federation and the United States (0.397 (A1) and 0.603 (A2), and 0.615 (A1) and 0.385 (A2), respectively) were detected. These significant population differences deserve serious attention and a detailed analysis of polymorphism in other serotonin system genes in different populations of Russian Federation. © Pleiades Publishing, Ltd., 2012.

U2 - 10.1134/S2079057012030149

DO - 10.1134/S2079057012030149

M3 - Article

VL - 2

SP - 247

EP - 252

JO - Advances in Gerontology

JF - Advances in Gerontology

SN - 2079-0570

IS - 3

ER -

ID: 5548910