Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy › SPbU Researchers Portal

Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy

Research output: Contribution to journal › Article

Department of Organic Chemistry

Links

https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84941551184&origin=inward

DOI

https://doi.org/10.1021/acs.jmedchem.5b00680
Other version

G. Papeo
H. Posteri
D. Borghi
A.A. Busel
F. Caprera
E. Casale
M. Ciomei
A. Cirla
E. Corti
M. D'Anello
M. Fasolini
B. Forte
A. Galvani
A. Isacchi
A. Khvat
R. Lupi
P. Orsini
R. Perego
E. Pesenti
D. Pezzetta
S. Rainoldi
F. Riccardi-Sirtori
A. Scolaro
F. Sola
F. Zuccotto
E.R. Felder
D. Donati
A. Montagnoli

Original language	English
Pages (from-to)	6875-6898
Journal	Journal of Medicinal Chemistry
Issue number	17
DOIs	https://doi.org/10.1021/acs.jmedchem.5b00680
State	Published - 2015

ID: 4005084