Diagnostic accuracy of mammography and mammoscintigraphy with 99m Tc-MIBI in detection of minimal breast cancer. / Chernaya, A. V.; Kanaev, S. V.; Krzhivitsky, P. I.; Krivorotko, P. I.; Busko, E. A.
In: Voprosy Onkologii, Vol. 63, No. 2, 01.01.2017, p. 274-280.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Diagnostic accuracy of mammography and mammoscintigraphy with 99m Tc-MIBI in detection of minimal breast cancer
AU - Chernaya, A. V.
AU - Kanaev, S. V.
AU - Krzhivitsky, P. I.
AU - Krivorotko, P. I.
AU - Busko, E. A.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - In 437 primary patients with breast cancer (BC) we compared diagnostic accuracy of mammography (MG) and mammoscintigraphy (MCG) with 99mTc-MIBI. All women, included in the study, had lesions suspicious for BC. In 108 suspicious lesions were less than 10 mm in diameter. On histology 33 (30,5%) patients had invasive BC, 20 (18,5%) - noninvasive BC, 6 (5,6%) - lobular carcinoma, 2 (1,9%) - mucinous BC, 8 (7,4%) - fibroadenoma and in remained 39 cases (36,1%) - localised fibrosis. In the group of women with lesions below 10 mm sensitivity, specificity and accuracy of MG in diagnosis of BC were 72%, 74%, 73%, for MCG - 62%, 51%, 57%. Combination of MG and MCG helped to increase sensitivity to 93,4%. In 53 women with dense breasts sensitivity, specificity and accuracy of MG were 40%, 71,4%, 64%; for MCG two times higher (82%) with specificity of 55% and 60% accuracy. Combination of MG and MCG allowed increasing the sensitivity of diagnosis of minimal BC 2 times more (up to 91%).
AB - In 437 primary patients with breast cancer (BC) we compared diagnostic accuracy of mammography (MG) and mammoscintigraphy (MCG) with 99mTc-MIBI. All women, included in the study, had lesions suspicious for BC. In 108 suspicious lesions were less than 10 mm in diameter. On histology 33 (30,5%) patients had invasive BC, 20 (18,5%) - noninvasive BC, 6 (5,6%) - lobular carcinoma, 2 (1,9%) - mucinous BC, 8 (7,4%) - fibroadenoma and in remained 39 cases (36,1%) - localised fibrosis. In the group of women with lesions below 10 mm sensitivity, specificity and accuracy of MG in diagnosis of BC were 72%, 74%, 73%, for MCG - 62%, 51%, 57%. Combination of MG and MCG helped to increase sensitivity to 93,4%. In 53 women with dense breasts sensitivity, specificity and accuracy of MG were 40%, 71,4%, 64%; for MCG two times higher (82%) with specificity of 55% and 60% accuracy. Combination of MG and MCG allowed increasing the sensitivity of diagnosis of minimal BC 2 times more (up to 91%).
KW - Breast cancer
KW - Mammography
KW - Mammoscintigraphy
KW - Minimal cancer
UR - http://www.scopus.com/inward/record.url?scp=85020436106&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85020436106
VL - 63
SP - 274
EP - 280
JO - Вопросы онкологии
JF - Вопросы онкологии
SN - 0507-3758
IS - 2
ER -
ID: 38684427