Gold nanoparticles are synthesized via laser ablation of a gold target in a liquid. The constants that characterize the efficiency of porphyrins and fullerenes bonding with gold nanoparticles are determined using a modified Stern–Volmer equation. The results from luminescence quenching measurements are presented. It is found that the efficiency of bonding depends on whether there are functional groups in the molecular fragments. Porphyrin containing para-bromphenyl groups at the meso positions of the porphyrin core has the highest affinity for the surfaces of gold nanoparticles.