TY - JOUR

T1 - Deep eutectic solvents with low viscosity for automation of liquid-phase microextraction based on lab-in-syringe system: Separation of Sudan dyes

AU - Шишов, Андрей Юрьевич

AU - Почивалов, Алексей Сергеевич

AU - Дубровский, Иван Сергеевич

AU - Булатов, Андрей Васильевич

PY - 2023/4/1

Y1 - 2023/4/1

N2 - In the work limitations of deep eutectic solvents in the flow-based analysis are discussed. Deep eutectic solvents based on terpenes and fatty acids with low viscosity were studied as extraction solvents for liquid-liquid microextraction into a lab-in-syringe system for the first time. As a result an automated deep eutectic solvent-based microextraction approach was proposed. The procedure involved aspiration of deep eutectic solvent (based on terpene and fatty acid) and aqueous sample solution followed by phases mixing by a magnetic stirrer inside a syringe of flow system. After phase separation the extract phase was transferred from the syringe into a vial followed by analysis by a high-performance liquid chromatography with diode-array detection. The determination of Sudan I, Sudan II and Sudan III in chili-based sauces was considered as an analytical task. The mass-transfer intensification performed by the magnetic stirring inside the syringe allowed to perform fast (2 min) and efficient (extraction recoveries 87–95%) extraction. The limits of detection, calculated from a blank test based on 3σ, were from 0.003 to 0.005 mg kg−1, RSD was

AB - In the work limitations of deep eutectic solvents in the flow-based analysis are discussed. Deep eutectic solvents based on terpenes and fatty acids with low viscosity were studied as extraction solvents for liquid-liquid microextraction into a lab-in-syringe system for the first time. As a result an automated deep eutectic solvent-based microextraction approach was proposed. The procedure involved aspiration of deep eutectic solvent (based on terpene and fatty acid) and aqueous sample solution followed by phases mixing by a magnetic stirrer inside a syringe of flow system. After phase separation the extract phase was transferred from the syringe into a vial followed by analysis by a high-performance liquid chromatography with diode-array detection. The determination of Sudan I, Sudan II and Sudan III in chili-based sauces was considered as an analytical task. The mass-transfer intensification performed by the magnetic stirring inside the syringe allowed to perform fast (2 min) and efficient (extraction recoveries 87–95%) extraction. The limits of detection, calculated from a blank test based on 3σ, were from 0.003 to 0.005 mg kg−1, RSD was

KW - Chili-based sauce

KW - Deep eutectic solvent

KW - HPLC-DAD

KW - Lab-in-syringe

KW - Liquid-phase microextraction

KW - Sudan dyes

KW - Viscosity

UR - https://www.mendeley.com/catalogue/1f4f72a9-b695-3cd4-8895-67d830761ad2/

U2 - 10.1016/j.talanta.2022.124243

DO - 10.1016/j.talanta.2022.124243

M3 - Article

VL - 255

JO - Talanta

JF - Talanta

SN - 0039-9140

M1 - 124243

ER -