TY - JOUR

T1 - Deep eutectic mixture membrane-based microextraction

T2 - HPLC-FLD determination of phenols in smoked food samples

AU - Shishov, Andrey

AU - Gagarionova, Svetlana

AU - Bulatov, Andrey

N1 - Funding Information: Andrey Shishov gratefully acknowledges financial support for research from Russian Scientific Foundation (project no. 18-73-00111). Scientific research was partially performed at the Educational Resource Center of the Research Park of Saint Petersburg State University . Appendix A Publisher Copyright: © 2019 Elsevier Ltd Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2020/6/1

Y1 - 2020/6/1

N2 - A novel approach for effective sample pretreatment of food was developed. This approach was based on in situ deep eutectic mixtures formation between analytes (hydrogen bond donors) and choline chloride (a hydrogen bond acceptor) supported in a hydrophilic porous membrane. By this action, the analytes were extracted and retained into the hydrophilic porous membrane. Finally, the hydrophilic porous membrane containing the analytes was transferred into an aqueous phase and back-extraction occurred due to deep eutectic mixture decomposition in the aqueous phase. The developed approach was applied to the HPLC-FLD determination of phenols (phenol, o-cresol, p-cresol, eugenol, isoeugenol and guaiacol) in smoked food samples. The limits of detection, calculated from a blank test based on 3σ, were 0.3 µg kg−1 for phenol, o-cresol, p-cresol; 0.6 µg kg−1 for eugenol, isoeugenol; and 1 µg kg−1 for guaiacol.

AB - A novel approach for effective sample pretreatment of food was developed. This approach was based on in situ deep eutectic mixtures formation between analytes (hydrogen bond donors) and choline chloride (a hydrogen bond acceptor) supported in a hydrophilic porous membrane. By this action, the analytes were extracted and retained into the hydrophilic porous membrane. Finally, the hydrophilic porous membrane containing the analytes was transferred into an aqueous phase and back-extraction occurred due to deep eutectic mixture decomposition in the aqueous phase. The developed approach was applied to the HPLC-FLD determination of phenols (phenol, o-cresol, p-cresol, eugenol, isoeugenol and guaiacol) in smoked food samples. The limits of detection, calculated from a blank test based on 3σ, were 0.3 µg kg−1 for phenol, o-cresol, p-cresol; 0.6 µg kg−1 for eugenol, isoeugenol; and 1 µg kg−1 for guaiacol.

KW - Deep eutectic mixture

KW - Food samples

KW - HPLC-FLD

KW - Membrane-based liquid phase microextraction

KW - Phenols

KW - Limit of Detection

KW - Membranes, Artificial

KW - Food Preservation/methods

KW - Choline/chemistry

KW - Solvents/chemistry

KW - Phenols/analysis

KW - Hydrogen Bonding

KW - Chromatography, High Pressure Liquid/methods

KW - Liquid Phase Microextraction/instrumentation

KW - Hydrophobic and Hydrophilic Interactions

KW - Food Analysis/instrumentation

KW - AROMATIC-HYDROCARBONS PAH

KW - LIQUID-PHASE MICROEXTRACTION

KW - PRECONCENTRATION

KW - SUBSTANCES

KW - GREEN

KW - EXTRACTION

KW - FLUOROQUINOLONES

KW - SOLVENT-MICROEXTRACTION

UR - http://www.scopus.com/inward/record.url?scp=85077739098&partnerID=8YFLogxK

U2 - 10.1016/j.foodchem.2019.126097

DO - 10.1016/j.foodchem.2019.126097

M3 - Article

C2 - 31945551

AN - SCOPUS:85077739098

VL - 314

JO - Food Chemistry

JF - Food Chemistry

SN - 0308-8146

M1 - 126097

ER -