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Cytogenetic Effect of Volatile Components of Urine of Mature Animals on Bone Marrow Cells of Young Female House Mice Mus musculus L. / Daev, E. V.; Poluekhina, E. V.

In: Russian Journal of Genetics, Vol. 32, No. 3, 01.12.1996, p. 357-360.

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@article{bfa1003b4af84e23bf6494acc128274e,
title = "Cytogenetic Effect of Volatile Components of Urine of Mature Animals on Bone Marrow Cells of Young Female House Mice Mus musculus L",
abstract = "Effects of volatile components of the urine (VCU) of mature male and female CBA/LacStoRap mice on proliferating bone marrow cells in young females of the same line were analyzed. To estimate the effects of VCU, cytogenetic analysis of mitotic disturbances in anaphase-telophase cells was performed. The overall frequency of mitotic disturbances such as chromosome bridges, fragments, retarded chromosomes, and multiple rearrangements was assessed. The overall frequency of mitotic disturbances in young female mice treated with VCU from mature females for 2 h significantly increased 24 h after exposure. The spectrum of mitotic disturbances was also affected by the VCU treatment. After exposure to VCU from mature males, no significant variation of parameters analyzed was detected in young female mice. The possible mechanisms and role of specific effects of VCU from animals of different sexes on young female house mice are discussed.",
author = "Daev, {E. V.} and Poluekhina, {E. V.}",
year = "1996",
month = dec,
day = "1",
language = "English",
volume = "32",
pages = "357--360",
journal = "Russian Journal of Genetics",
issn = "1022-7954",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "3",

}

RIS

TY - JOUR

T1 - Cytogenetic Effect of Volatile Components of Urine of Mature Animals on Bone Marrow Cells of Young Female House Mice Mus musculus L

AU - Daev, E. V.

AU - Poluekhina, E. V.

PY - 1996/12/1

Y1 - 1996/12/1

N2 - Effects of volatile components of the urine (VCU) of mature male and female CBA/LacStoRap mice on proliferating bone marrow cells in young females of the same line were analyzed. To estimate the effects of VCU, cytogenetic analysis of mitotic disturbances in anaphase-telophase cells was performed. The overall frequency of mitotic disturbances such as chromosome bridges, fragments, retarded chromosomes, and multiple rearrangements was assessed. The overall frequency of mitotic disturbances in young female mice treated with VCU from mature females for 2 h significantly increased 24 h after exposure. The spectrum of mitotic disturbances was also affected by the VCU treatment. After exposure to VCU from mature males, no significant variation of parameters analyzed was detected in young female mice. The possible mechanisms and role of specific effects of VCU from animals of different sexes on young female house mice are discussed.

AB - Effects of volatile components of the urine (VCU) of mature male and female CBA/LacStoRap mice on proliferating bone marrow cells in young females of the same line were analyzed. To estimate the effects of VCU, cytogenetic analysis of mitotic disturbances in anaphase-telophase cells was performed. The overall frequency of mitotic disturbances such as chromosome bridges, fragments, retarded chromosomes, and multiple rearrangements was assessed. The overall frequency of mitotic disturbances in young female mice treated with VCU from mature females for 2 h significantly increased 24 h after exposure. The spectrum of mitotic disturbances was also affected by the VCU treatment. After exposure to VCU from mature males, no significant variation of parameters analyzed was detected in young female mice. The possible mechanisms and role of specific effects of VCU from animals of different sexes on young female house mice are discussed.

UR - http://www.scopus.com/inward/record.url?scp=1842480940&partnerID=8YFLogxK

M3 - Article

C2 - 8723632

AN - SCOPUS:0030100022

VL - 32

SP - 357

EP - 360

JO - Russian Journal of Genetics

JF - Russian Journal of Genetics

SN - 1022-7954

IS - 3

ER -

ID: 42209327