Research output: Contribution to journal › Article › peer-review
Cytogenetic Effect of Volatile Components of Urine of Mature Animals on Bone Marrow Cells of Young Female House Mice Mus musculus L. / Daev, E. V.; Poluekhina, E. V.
In: Russian Journal of Genetics, Vol. 32, No. 3, 01.12.1996, p. 357-360.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Cytogenetic Effect of Volatile Components of Urine of Mature Animals on Bone Marrow Cells of Young Female House Mice Mus musculus L
AU - Daev, E. V.
AU - Poluekhina, E. V.
PY - 1996/12/1
Y1 - 1996/12/1
N2 - Effects of volatile components of the urine (VCU) of mature male and female CBA/LacStoRap mice on proliferating bone marrow cells in young females of the same line were analyzed. To estimate the effects of VCU, cytogenetic analysis of mitotic disturbances in anaphase-telophase cells was performed. The overall frequency of mitotic disturbances such as chromosome bridges, fragments, retarded chromosomes, and multiple rearrangements was assessed. The overall frequency of mitotic disturbances in young female mice treated with VCU from mature females for 2 h significantly increased 24 h after exposure. The spectrum of mitotic disturbances was also affected by the VCU treatment. After exposure to VCU from mature males, no significant variation of parameters analyzed was detected in young female mice. The possible mechanisms and role of specific effects of VCU from animals of different sexes on young female house mice are discussed.
AB - Effects of volatile components of the urine (VCU) of mature male and female CBA/LacStoRap mice on proliferating bone marrow cells in young females of the same line were analyzed. To estimate the effects of VCU, cytogenetic analysis of mitotic disturbances in anaphase-telophase cells was performed. The overall frequency of mitotic disturbances such as chromosome bridges, fragments, retarded chromosomes, and multiple rearrangements was assessed. The overall frequency of mitotic disturbances in young female mice treated with VCU from mature females for 2 h significantly increased 24 h after exposure. The spectrum of mitotic disturbances was also affected by the VCU treatment. After exposure to VCU from mature males, no significant variation of parameters analyzed was detected in young female mice. The possible mechanisms and role of specific effects of VCU from animals of different sexes on young female house mice are discussed.
UR - http://www.scopus.com/inward/record.url?scp=1842480940&partnerID=8YFLogxK
M3 - Article
C2 - 8723632
AN - SCOPUS:0030100022
VL - 32
SP - 357
EP - 360
JO - Russian Journal of Genetics
JF - Russian Journal of Genetics
SN - 1022-7954
IS - 3
ER -
ID: 42209327