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Corneal confocal microscopy in the diagnosis of small fiber neuropathy : Faster, easier, and more efficient than skin biopsy? / Lukashenko, Mariia V.; Gavrilova, Natalia Y.; Bregovskaya, Anna V.; Soprun, Lidiia A.; Churilov, Leonid P.; Petropoulos, Ioannis N.; Malik, Rayaz A.; Shoenfeld, Yehuda.

In: Pathophysiology, Vol. 29, No. 1, 01.2022, p. 1-8.

Research output: Contribution to journal › Review article › peer-review

Harvard

Lukashenko, MV, Gavrilova, NY, Bregovskaya, AV, Soprun, LA, Churilov, LP, Petropoulos, IN, Malik, RA & Shoenfeld, Y 2022, 'Corneal confocal microscopy in the diagnosis of small fiber neuropathy: Faster, easier, and more efficient than skin biopsy?', Pathophysiology, vol. 29, no. 1, pp. 1-8. https://doi.org/10.3390/pathophysiology29010001

APA

Lukashenko, M. V., Gavrilova, N. Y., Bregovskaya, A. V., Soprun, L. A., Churilov, L. P., Petropoulos, I. N., Malik, R. A., & Shoenfeld, Y. (2022). Corneal confocal microscopy in the diagnosis of small fiber neuropathy: Faster, easier, and more efficient than skin biopsy? Pathophysiology, 29(1), 1-8. https://doi.org/10.3390/pathophysiology29010001

Vancouver

Lukashenko MV, Gavrilova NY, Bregovskaya AV, Soprun LA, Churilov LP, Petropoulos IN et al. Corneal confocal microscopy in the diagnosis of small fiber neuropathy: Faster, easier, and more efficient than skin biopsy? Pathophysiology. 2022 Jan;29(1):1-8. https://doi.org/10.3390/pathophysiology29010001

Author

Lukashenko, Mariia V. ; Gavrilova, Natalia Y. ; Bregovskaya, Anna V. ; Soprun, Lidiia A. ; Churilov, Leonid P. ; Petropoulos, Ioannis N. ; Malik, Rayaz A. ; Shoenfeld, Yehuda. / Corneal confocal microscopy in the diagnosis of small fiber neuropathy : Faster, easier, and more efficient than skin biopsy?. In: Pathophysiology. 2022 ; Vol. 29, No. 1. pp. 1-8.

BibTeX

@article{2deeff4c689a457089fee7ffed49eb12,
title = "Corneal confocal microscopy in the diagnosis of small fiber neuropathy: Faster, easier, and more efficient than skin biopsy?",
abstract = "Chronic pain may affect 30–50% of the world{\textquoteright}s population and an important cause is small fiber neuropathy (SFN). Recent research suggests that autoimmune diseases may be one of the most common causes of small nerve fiber damage. There is low awareness of SFN among patients and clinicians and it is difficult to diagnose as routine electrophysiological methods only detect large fiber abnormalities, and specialized small fiber tests, like skin biopsy and quantitative sensory testing, are not routinely available. Corneal confocal microscopy (CCM) is a rapid, non-invasive, reproducible method for quantifying small nerve fiber degeneration and regeneration, and could be an important tool for diagnosing SFN. This review considers the advantages and disadvantages of CCM and highlights the evolution of this technique from a research tool to a diagnostic test for small fiber damage, which can be a valuable contribution to the study and management of autoimmune disease.",
keywords = "Autoimmune neuropathies, Autoimmunity, Confocal microscopy (CM), Cornea, Sarcoidosis, Sjogren{\textquoteright}s syndrome, Skin biopsy, Small fiber neuropathy (SFN)",
author = "Lukashenko, {Mariia V.} and Gavrilova, {Natalia Y.} and Bregovskaya, {Anna V.} and Soprun, {Lidiia A.} and Churilov, {Leonid P.} and Petropoulos, {Ioannis N.} and Malik, {Rayaz A.} and Yehuda Shoenfeld",
note = "Lukashenko, M.V.; Gavrilova, N.Y.; Bregovskaya, A.V.; Soprun, L.A.; Churilov, L.P.; Petropoulos, I.N.; Malik, R.A.; Shoenfeld, Y. Corneal Confocal Microscopy in the Diagnosis of Small Fiber Neuropathy: Faster, Easier, and More Efficient Than Skin Biopsy? Pathophysiology 2022, 29, 1-8. https://doi.org/10.3390/pathophysiology29010001",
year = "2022",
month = jan,
doi = "10.3390/pathophysiology29010001",
language = "English",
volume = "29",
pages = "1--8",
journal = "Pathophysiology",
issn = "0928-4680",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Corneal confocal microscopy in the diagnosis of small fiber neuropathy

T2 - Faster, easier, and more efficient than skin biopsy?

AU - Lukashenko, Mariia V.

AU - Gavrilova, Natalia Y.

AU - Bregovskaya, Anna V.

AU - Soprun, Lidiia A.

AU - Churilov, Leonid P.

AU - Petropoulos, Ioannis N.

AU - Malik, Rayaz A.

AU - Shoenfeld, Yehuda

N1 - Lukashenko, M.V.; Gavrilova, N.Y.; Bregovskaya, A.V.; Soprun, L.A.; Churilov, L.P.; Petropoulos, I.N.; Malik, R.A.; Shoenfeld, Y. Corneal Confocal Microscopy in the Diagnosis of Small Fiber Neuropathy: Faster, Easier, and More Efficient Than Skin Biopsy? Pathophysiology 2022, 29, 1-8. https://doi.org/10.3390/pathophysiology29010001

PY - 2022/1

Y1 - 2022/1

N2 - Chronic pain may affect 30–50% of the world’s population and an important cause is small fiber neuropathy (SFN). Recent research suggests that autoimmune diseases may be one of the most common causes of small nerve fiber damage. There is low awareness of SFN among patients and clinicians and it is difficult to diagnose as routine electrophysiological methods only detect large fiber abnormalities, and specialized small fiber tests, like skin biopsy and quantitative sensory testing, are not routinely available. Corneal confocal microscopy (CCM) is a rapid, non-invasive, reproducible method for quantifying small nerve fiber degeneration and regeneration, and could be an important tool for diagnosing SFN. This review considers the advantages and disadvantages of CCM and highlights the evolution of this technique from a research tool to a diagnostic test for small fiber damage, which can be a valuable contribution to the study and management of autoimmune disease.

AB - Chronic pain may affect 30–50% of the world’s population and an important cause is small fiber neuropathy (SFN). Recent research suggests that autoimmune diseases may be one of the most common causes of small nerve fiber damage. There is low awareness of SFN among patients and clinicians and it is difficult to diagnose as routine electrophysiological methods only detect large fiber abnormalities, and specialized small fiber tests, like skin biopsy and quantitative sensory testing, are not routinely available. Corneal confocal microscopy (CCM) is a rapid, non-invasive, reproducible method for quantifying small nerve fiber degeneration and regeneration, and could be an important tool for diagnosing SFN. This review considers the advantages and disadvantages of CCM and highlights the evolution of this technique from a research tool to a diagnostic test for small fiber damage, which can be a valuable contribution to the study and management of autoimmune disease.

KW - Autoimmune neuropathies

KW - Autoimmunity

KW - Confocal microscopy (CM)

KW - Cornea

KW - Sarcoidosis

KW - Sjogren’s syndrome

KW - Skin biopsy

KW - Small fiber neuropathy (SFN)

UR - http://www.scopus.com/inward/record.url?scp=85121980239&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/3ec3d4ec-8ba6-3533-809d-afb65c0a1a2c/

U2 - 10.3390/pathophysiology29010001

DO - 10.3390/pathophysiology29010001

M3 - Review article

C2 - 35366285

AN - SCOPUS:85121980239

VL - 29

SP - 1

EP - 8

JO - Pathophysiology

JF - Pathophysiology

SN - 0928-4680

IS - 1

ER -

ID: 91126834