Research output: Contribution to journal › Article › peer-review
Stepwise coupling of N-Boc-protected beta-aminoethanols or beta-mercaptoethylamines with various alpha-diazoacetates provides a new, unified approach to constructing (thio)morpholin-3-ones. The process involves a Rh-2(esp)(2)-catalyzed X-H insertion reaction, Boc group removal and ambient-temperature lactamization and is conveniently conducted in one-pot format.
Original language | English |
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Pages (from-to) | 7432-7438 |
Number of pages | 7 |
Journal | European Journal of Organic Chemistry |
Volume | 2019 |
Issue number | 45 |
Early online date | 11 Oct 2019 |
DOIs | |
State | Published - 8 Dec 2019 |
ID: 49497474